Sirt6 loss activates Got1 and facilitates cleft palate through abnormal activating glycolysis.
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| Title: | Sirt6 loss activates Got1 and facilitates cleft palate through abnormal activating glycolysis. |
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| Authors: | Wang X; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Zhao X; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Zheng X; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Peng X; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Chen J; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Wang Y; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Wang Z; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Meng M; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China., Du J; Laboratory of Orofacial Development, Laboratory of Molecular Signaling and Stem Cells Therapy, Molecular Laboratory for Gene Therapy and Tooth Regeneration, Beijing Key Laboratory of Tooth Re-generation and Function Reconstruction, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China. juandug@ccmu.edu.cn.; Department of geriatric dentistry, Capital Medical University School of Stomatology, Fanjiacun Road No.9, Beijing, 100070, China. juandug@ccmu.edu.cn. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Mar 06; Vol. 16 (1), pp. 159. Date of Electronic Publication: 2025 Mar 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-025-07465-8 |
