Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody.
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| Title: | Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody. |
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| Authors: | Ständer SHD; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Reboul CF; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Monash University, Clayton, VIC, Australia.; National Institutes of Health, National Cancer Institute-Frederick Campus, Fredrick, MD, USA., Le SN; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Monash University, Clayton, VIC, Australia.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Williams DE; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Chandler PG; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Costa MGS; Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil., Hoke DE; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Jimma JDT; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark., Fodor J; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; The Centre for Brain, Mind and Markets, The University of Melbourne, Melbourne, VIC, Australia., Fenalti G; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Mannering SI; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Melbourne, VIC, Australia., Porebski BT; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Schofield P; Garvan Institute of Medical Research, UNSW Sydney, Darlinghurst, NSW, Australia., Christ D; Garvan Institute of Medical Research, UNSW Sydney, Darlinghurst, NSW, Australia., Buckle M; LBPA, ENS de Paris-Saclay, UMR 8113 CNRS, Université Paris-Saclay 4, Gif-sur-Yvette, France., McGowan S; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Elmlund D; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Monash University, Clayton, VIC, Australia., Rand KD; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Copenhagen, Denmark. kasper.rand@sund.ku.dk., Buckle AM; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia. ashley.buckle@monash.edu.; San Diego Biomedical Research Institute, San Diego, CA, USA. ashley.buckle@monash.edu. |
| Source: | Nature communications [Nat Commun] 2025 Mar 07; Vol. 16 (1), pp. 2275. Date of Electronic Publication: 2025 Mar 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-57492-4 |
