CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes.

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Title: CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes.
Authors: Sun Y; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany., Kronenberg NM; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany., Sethi SK; Pediatric Nephrology and Pediatric Kidney Transplantation, Medanta Kidney and Urology Institute, The Medicity Hospital, Gurgaon, India., Dash SN; Division of Nephrology, Department of Medicine, Duke University, Durham, North Carolina, United States.; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Kovalik ME; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Sempowski B; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Strickland S; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Raina R; Cleveland Clinic Akron General Medical Center, Akron Nephrology Associates, Akron, Ohio, United States., Sperati CJ; Division of Nephrology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States., Tian X; Division of Nephrology, Department of Medicine, Yale University, New Haven, Connecticut, United States., Ishibe S; Division of Nephrology, Department of Medicine, Yale University, New Haven, Connecticut, United States., Hall G; Division of Nephrology, Department of Medicine, Duke University, Durham, North Carolina, United States.; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States., Gather MC; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany.; Centre of Biophotonics, SUPA, School of Physics and Astronomy, University of St Andrews, St Andrews, United Kingdom.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2025 Apr 01; Vol. 328 (4), pp. F578-F595. Date of Electronic Publication: 2025 Mar 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
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  Data: CRB2 depletion induces YAP signaling and disrupts mechanosensing in podocytes.
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  Data: <searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kronenberg+NM%22">Kronenberg NM</searchLink>; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Sethi+SK%22">Sethi SK</searchLink>; Pediatric Nephrology and Pediatric Kidney Transplantation, Medanta Kidney and Urology Institute, The Medicity Hospital, Gurgaon, India.<br /><searchLink fieldCode="AU" term="%22Dash+SN%22">Dash SN</searchLink>; Division of Nephrology, Department of Medicine, Duke University, Durham, North Carolina, United States.; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Kovalik+ME%22">Kovalik ME</searchLink>; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Sempowski+B%22">Sempowski B</searchLink>; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Strickland+S%22">Strickland S</searchLink>; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Raina+R%22">Raina R</searchLink>; Cleveland Clinic Akron General Medical Center, Akron Nephrology Associates, Akron, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Sperati+CJ%22">Sperati CJ</searchLink>; Division of Nephrology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Tian+X%22">Tian X</searchLink>; Division of Nephrology, Department of Medicine, Yale University, New Haven, Connecticut, United States.<br /><searchLink fieldCode="AU" term="%22Ishibe+S%22">Ishibe S</searchLink>; Division of Nephrology, Department of Medicine, Yale University, New Haven, Connecticut, United States.<br /><searchLink fieldCode="AU" term="%22Hall+G%22">Hall G</searchLink>; Division of Nephrology, Department of Medicine, Duke University, Durham, North Carolina, United States.; Duke Molecular Physiology Institute, Duke University, Durham, North Carolina, United States.<br /><searchLink fieldCode="AU" term="%22Gather+MC%22">Gather MC</searchLink>; Humboldt Centre for Nano- and Biophotonics, Department of Chemistry, University of Cologne, Cologne, Germany.; Centre of Biophotonics, SUPA, School of Physics and Astronomy, University of St Andrews, St Andrews, United Kingdom.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Disease (CECAD), University of Cologne, Cologne, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Physiological+Society%22">American Physiological Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100901990 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1522-1466 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215221466%22">15221466 </searchLink><i>NLM ISO Abbreviation: </i>Am J Physiol Renal Physiol <i>Subsets: </i>MEDLINE
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        Value: 10.1152/ajprenal.00318.2024
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