The Spectrum of IDH- and H3-Wildtype High-Grade Glioma Subgroups Occurring across Teenage and Young Adult Patient Populations.

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Title: The Spectrum of IDH- and H3-Wildtype High-Grade Glioma Subgroups Occurring across Teenage and Young Adult Patient Populations.
Authors: Pereira R; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom., Mackay A; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom., Grabovska Y; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom., Bradley A; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Bloom T; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Nicoll J; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Boche D; Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Procter J; Neuropathology and Pathology Research, Royal Preston Hospital, Preston, United Kingdom., Maybury M; Oncology Services Group, Queensland Children' Hospital, Brisbane, Australia.; Child Health Research Centre, The University of Queensland, Brisbane, Australia., Schagen J; Child Health Research Centre, The University of Queensland, Brisbane, Australia., Walker L; Department of Cellular Pathology, Northern Care Alliance, Salford, United Kingdom.; Geoffrey Jefferson Brain Research Centre, Division of Neuroscience, School of Biology, University of Manchester, Manchester, United Kingdom., Roncaroli F; Department of Cellular Pathology, Northern Care Alliance, Salford, United Kingdom.; Geoffrey Jefferson Brain Research Centre, Division of Neuroscience, School of Biology, University of Manchester, Manchester, United Kingdom., Karabatsou K; Department of Neurosurgery, Manchester Centre of Clinical Neuroscience, Northern Care Alliance, Salford, United Kingdom., Ogunbiyi O; Neuropathology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom., van Dalen T; Neurosurgery Department, National Hospital for Neurology and Neurosurgery, UCLH, London, United Kingdom., Sidpra J; Paediatric Neuro Oncology, UCL Great Ormond Street Institute of Child Health, London, United Kingdom., Rossi S; Sabrina Rossi. Pathology Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy., Miele E; Pediatric Onco-Haematology, Cell Therapy, Gene Therapies and Hematopoietic Transplant, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy., Ziegler DS; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, Australia., Shi Z; Neurosurgery, Fudan University, Shanghai, China., Jacques TS; Geoffrey Jefferson Brain Research Centre, Division of Neuroscience, School of Biology, University of Manchester, Manchester, United Kingdom., Hargrave D; Paediatric Neuro Oncology, UCL Great Ormond Street Institute of Child Health, London, United Kingdom., Zebian B; Neurosurgery Department, King's College Hospital, London, United Kingdom., Bleil C; Neurosurgery Department, King's College Hospital, London, United Kingdom., Yates J; Department of Cellular Pathology, University Hospital Southampton NHS Trust, Southampton, United Kingdom., Norton E; Department of Cellular Pathology, University Hospital Southampton NHS Trust, Southampton, United Kingdom., Mandeville H; Department of Paediatric and Teenager & Young Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom., Creak A; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom.; Department of Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom., Welsh L; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom.; Department of Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom., Marshall L; Department of Paediatric and Teenager & Young Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom.; Paediatric and Adolescent Oncology Drug Development Unit, The Royal Marsden NHS Foundation Trust, London, United Kingdom., Carceller F; Department of Paediatric and Teenager & Young Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom., Vaidya SJ; Department of Paediatric and Teenager & Young Adult Neuro-Oncology, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.; Division of Clinical Studies, The Institute of Cancer Research, London, United Kingdom., Reisz Z; Neuropathology Department, King's College Hospital, London, United Kingdom., Al-Sarraj S; Neuropathology Department, King's College Hospital, London, United Kingdom., Mastronuzzi A; Pediatric Onco-Hematology, Cell Therapy, Gene Therapies and Hematopoietic Transplant, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy., Carai A; Neurosurgery Unit, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy., Vinci M; Paediatric Cancer Genetics and Epigenetics Research Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy., Kurian KM; University of Bristol Brain Tumour Research Centre, Neuropathology, Southmead Hospital, Bristol, United Kingdom., Ng HK; Chinese University of Hong Kong, Hong Kong, China., Brandner S; Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, and Queen Square Institute of Neurology, London, United Kingdom., Jones C; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom., Clarke M; Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.; Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, and Queen Square Institute of Neurology, London, United Kingdom.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Aug 01; Vol. 31 (15), pp. 3259-3275.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-24-1256