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Long-term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome.

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Title: Long-term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome.
Authors: Scheffer IE; Austin Hospital and Royal Children's Hospital, Florey and Murdoch Children's Research Institutes, University of Melbourne, Melbourne, Victoria, Australia., Nabbout R; Member of the European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, Institut Imagine, INSERM U1163, Université Paris Cité, Paris, France., Lagae L; Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium., Devinsky O; NYU Langone Medical Center, New York City, New York, USA., Auvin S; Member of the European Reference Network EpiCARE, APHP, Centre de Référence Epilepsies Rares, Hôpital Universitaire Robert-Debré, Paris, France.; Université Paris-Cité, INSERM Neuro Diderot, Paris, France.; Institut Universitaire de France (IUF), Paris, France., Thiele EA; Massachusetts General Hospital, Boston, Massachusetts, USA., Wirrell EC; Mayo Clinic, Rochester, Minnesota, USA., Polster T; Krankenhaus Mara-Bethel Epilepsy Centre, Medical School OWL, Bielefeld University, Bielefeld, Germany., Specchio N; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Member of the European Reference Network EpiCARE, University Hospitals KU, Leuven, Belgium., Pringsheim M; Schön Klinik Vogtareuth, Vogtareuth, Germany.; PMU Salzburg, Salzburg, Austria.; German Heart Centre, TUM, Munich, Germany., Imai K; NHO Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan., Lock MD; Independent Statistical Consultant, Haiku, Hawaii, USA., Langlois M; UCB, Colombes, France., Roper RZ; UCB, Slough, UK., Lothe A; UCB, Colombes, France., Sullivan J; University of California San Francisco Weill Institute for Neurosciences, Benioff Children's Hospital, San Francisco, California, USA.
Source: Epilepsia [Epilepsia] 2025 Jun; Vol. 66 (6), pp. 1919-1932. Date of Electronic Publication: 2025 Mar 12.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Scheffer+IE%22">Scheffer IE</searchLink>; Austin Hospital and Royal Children's Hospital, Florey and Murdoch Children's Research Institutes, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nabbout+R%22">Nabbout R</searchLink>; Member of the European Reference Network EpiCARE, Reference Centre for Rare Epilepsies, Necker Enfants Malades Hospital, APHP, Institut Imagine, INSERM U1163, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lagae+L%22">Lagae L</searchLink>; Member of the European Reference Network EpiCARE, University of Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Devinsky+O%22">Devinsky O</searchLink>; NYU Langone Medical Center, New York City, New York, USA.<br /><searchLink fieldCode="AU" term="%22Auvin+S%22">Auvin S</searchLink>; Member of the European Reference Network EpiCARE, APHP, Centre de Référence Epilepsies Rares, Hôpital Universitaire Robert-Debré, Paris, France.; Université Paris-Cité, INSERM Neuro Diderot, Paris, France.; Institut Universitaire de France (IUF), Paris, France.<br /><searchLink fieldCode="AU" term="%22Thiele+EA%22">Thiele EA</searchLink>; Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Wirrell+EC%22">Wirrell EC</searchLink>; Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Polster+T%22">Polster T</searchLink>; Krankenhaus Mara-Bethel Epilepsy Centre, Medical School OWL, Bielefeld University, Bielefeld, Germany.<br /><searchLink fieldCode="AU" term="%22Specchio+N%22">Specchio N</searchLink>; Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.; Member of the European Reference Network EpiCARE, University Hospitals KU, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Pringsheim+M%22">Pringsheim M</searchLink>; Schön Klinik Vogtareuth, Vogtareuth, Germany.; PMU Salzburg, Salzburg, Austria.; German Heart Centre, TUM, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Imai+K%22">Imai K</searchLink>; NHO Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Lock+MD%22">Lock MD</searchLink>; Independent Statistical Consultant, Haiku, Hawaii, USA.<br /><searchLink fieldCode="AU" term="%22Langlois+M%22">Langlois M</searchLink>; UCB, Colombes, France.<br /><searchLink fieldCode="AU" term="%22Roper+RZ%22">Roper RZ</searchLink>; UCB, Slough, UK.<br /><searchLink fieldCode="AU" term="%22Lothe+A%22">Lothe A</searchLink>; UCB, Colombes, France.<br /><searchLink fieldCode="AU" term="%22Sullivan+J%22">Sullivan J</searchLink>; University of California San Francisco Weill Institute for Neurosciences, Benioff Children's Hospital, San Francisco, California, USA.
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  Data: <searchLink fieldCode="JN" term="%222983306R%22">Epilepsia</searchLink> [Epilepsia] 2025 Jun; Vol. 66 (6), pp. 1919-1932. <i>Date of Electronic Publication: </i>2025 Mar 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Blackwell+Science%22">Blackwell Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2983306R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-1167 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200139580%22">00139580 </searchLink><i>NLM ISO Abbreviation: </i>Epilepsia <i>Subsets: </i>MEDLINE
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        Value: 10.1111/epi.18342
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        Text: English
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        StartPage: 1919
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              Text: 2025 Jun
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