Female patients report comparable results to males after the implantation of an aragonite-based scaffold for the treatment of knee chondral and osteochondral defects: a gender-based analysis of a RCT at 4 years' follow-up.

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Title: Female patients report comparable results to males after the implantation of an aragonite-based scaffold for the treatment of knee chondral and osteochondral defects: a gender-based analysis of a RCT at 4 years' follow-up.
Authors: Kon E; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Milan, Italy.; IRCCS Humanitas Research Center, Via Manzoni 56, 20089, Rozzano, MI, Italy.; Department of Traumatology, Orthopaedics and Disaster Surgery, Sechenov First Moscow State Medical University (Sechenov University, 6-1 Bolshaya Pirogovskaya St, 119991, Moscow, Russia., De Caro F; Department of Orthopaedics, Istituto di Cura Città di Pavia, Pavia, Italy., Dasa V; Department of Orthopaedic Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA., M Scopp J; Joint Preservation Center, Peninsula Orthopaedic Associates, P.A., Salisbury, MD, USA., Di Matteo B; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090, Milan, Italy. berardo.dimatteo@gmail.com.; IRCCS Humanitas Research Center, Via Manzoni 56, 20089, Rozzano, MI, Italy. berardo.dimatteo@gmail.com.; Department of Traumatology, Orthopaedics and Disaster Surgery, Sechenov First Moscow State Medical University (Sechenov University, 6-1 Bolshaya Pirogovskaya St, 119991, Moscow, Russia. berardo.dimatteo@gmail.com., Flanigan D; The Ohio State University Wexner Medical Center, Columbus, OH, USA., Shabshin N; Division of Musculoskeletal Imaging, Department of Radiology, Penn Musculoskeletal Center, Philadelphia, PA, USA.; Emek Medical Center, Clalit Healthcare Services, Afula, Israel., Strickland S; Sports Medicine and Shoulder Service, Hospital for Special Surgery, Cornell University Medical College, New York, NY, USA., Altschuler N; Cartiheal Ltd, Tel Aviv, Israel.
Source: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology [J Orthop Traumatol] 2025 Mar 13; Vol. 26 (1), pp. 17. Date of Electronic Publication: 2025 Mar 13.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 101090931 Publication Model: Electronic Cited Medium: Internet ISSN: 1590-9999 (Electronic) Linking ISSN: 15909921 NLM ISO Abbreviation: J Orthop Traumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1590-9999
DOI:10.1186/s10195-025-00829-y