Afucosylated broadly neutralizing antibodies targeting the HIV envelope elicit enhanced NK-cell-mediated cytotoxicity against HIV-infected CD4+ T-cell and macrophage targets.
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| Title: | Afucosylated broadly neutralizing antibodies targeting the HIV envelope elicit enhanced NK-cell-mediated cytotoxicity against HIV-infected CD4+ T-cell and macrophage targets. |
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| Authors: | Wilhelm O; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, 792 Elizabeth St, Melbourne, VIC 3000, Australia., Jordan C; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia., Kek H; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Immunology, School of Translational Medicine, Monash University, Level 6, 99 Commercial Rd, Melbourne, VIC 3004, Australia., Brunton-O'Sullivan MM; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia., Rikard-Bell L; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, 792 Elizabeth St, Melbourne, VIC 3000, Australia., Ramanathan P; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, 792 Elizabeth St, Melbourne, VIC 3000, Australia., Chung AW; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, 792 Elizabeth St, Melbourne, VIC 3000, Australia., Poumbourios P; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Microbiology, Monash University, 19 Innovation Walk, Clayton, VIC 3800, Australia., Wines BD; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Immunology, School of Translational Medicine, Monash University, Level 6, 99 Commercial Rd, Melbourne, VIC 3004, Australia., Jaworowski A; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Infectious Diseases, Monash University, Level 2, 85 Commercial Rd, Melbourne, VIC 3004, Australia.; School of Health and Biomedical Sciences, RMIT University, Plenty Rd, Bundoora, VIC 3083, Australia., Hearps AC; Life Sciences Discipline, Burnet Institute, GPO Box 284, Melbourne, VIC 3004, Australia.; Department of Infectious Diseases, Monash University, Level 2, 85 Commercial Rd, Melbourne, VIC 3004, Australia.; Department of Infectious Diseases, University of Melbourne, 792 Elizabeth St, Melbourne, VIC 3000, Australia. |
| Source: | Journal of leukocyte biology [J Leukoc Biol] 2025 May 07; Vol. 117 (5). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 8405628 Publication Model: Print Cited Medium: Internet ISSN: 1938-3673 (Electronic) Linking ISSN: 07415400 NLM ISO Abbreviation: J Leukoc Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1938-3673 |
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| DOI: | 10.1093/jleuko/qiaf033 |
