Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization.

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Title: Telomere length in offspring is determined by mitochondrial-nuclear communication at fertilization.
Authors: Winstanley YE; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia., Rose RD; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.; Genea Fertility SA, St. Andrews Hospital, Adelaide, SA, Australia., Sobinoff AP; Telomere Length Regulation Unit, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW, Australia., Wu LL; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia., Adhikari D; Development and Stem Cells Program and Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia., Zhang QH; Development and Stem Cells Program and Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia., Wells JK; Telomere Length Regulation Unit, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW, Australia., Wong LH; Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne VIC, Australia., Szeto HH; Social Profit Network, Menlo Park, CA, 94025, USA., Piltz SG; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.; South Australian Health & Medical Research Institute, Adelaide, SA, Australia., Thomas PQ; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia.; South Australian Health & Medical Research Institute, Adelaide, SA, Australia., Febbraio MA; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Carroll J; Development and Stem Cells Program and Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia., Pickett HA; Telomere Length Regulation Unit, Children's Medical Research Institute, Faculty of Medicine and Health, University of Sydney, Westmead, NSW, Australia., Russell DL; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia., Robker RL; Robinson Research Institute, School of Biomedicine, The University of Adelaide, Adelaide, SA, Australia. Rebecca.robker@adelaide.edu.au.; Development and Stem Cells Program and Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia. Rebecca.robker@adelaide.edu.au.
Source: Nature communications [Nat Commun] 2025 Mar 14; Vol. 16 (1), pp. 2527. Date of Electronic Publication: 2025 Mar 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57794-7