Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations.
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| Title: | Superior preclinical efficacy of co-treatment with BRG1/BRM and FLT3 inhibitor against AML cells with FLT3 mutations. |
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| Authors: | Fiskus W; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Mill CP; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Piel J; Foghorn Therapeutics, Cambridge, MA, 02139, USA., Collins M; Foghorn Therapeutics, Cambridge, MA, 02139, USA., Hentemann M; Foghorn Therapeutics, Cambridge, MA, 02139, USA., Cuglievan B; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Birdwell CE; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Das K; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Hou H; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Davis JA; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Jain A; Baylor College of Medicine, Houston, TX, 77030, USA., Malovannaya A; Baylor College of Medicine, Houston, TX, 77030, USA., Kadia TM; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Daver N; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Sasaki K; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Takahashi K; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Hammond D; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Reville PK; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Flores LB; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Loghavi S; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Su X; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., DiNardo CD; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA., Bhalla KN; The University of Texas M.D. Anderson Cancer Center, Houston, TX, 77030, USA. kbhalla@mdanderson.org. |
| Source: | Blood cancer journal [Blood Cancer J] 2025 Mar 15; Vol. 15 (1), pp. 40. Date of Electronic Publication: 2025 Mar 15. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2044-5385 |
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| DOI: | 10.1038/s41408-025-01251-7 |
