Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas.

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Title: Systematic evaluation of single-cell multimodal data integration for comprehensive human reference atlas.
Authors: Acera-Mateos M; Josep Carreras Leukemia Research Institute, Barcelona, Spain.; University of Barcelona (UB), Barcelona, Spain., Adiconis X; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Li JK; Josep Carreras Leukemia Research Institute, Barcelona, Spain., Marchese D; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain., Caratù G; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain., Hon CC; Laboratory for Regulatory Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Tiwari P; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Kojima M; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Vieth B; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, 82152 Planegg, Germany., Murphy MA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Current affiliation: Osmo; New York, NY 10016, USA., Simmons SK; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Lefevre T; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.; KU Leuven Institute for Single Cell Omics (LISCO), University of Leuven, KU Leuven, Leuven, Belgium., Claes I; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.; KU Leuven Institute for Single Cell Omics (LISCO), University of Leuven, KU Leuven, Leuven, Belgium., O'Connor CL; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Menon R; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Otto EA; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Ando Y; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Vandereyken K; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.; KU Leuven Institute for Single Cell Omics (LISCO), University of Leuven, KU Leuven, Leuven, Belgium., Kretzler M; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Bitzer M; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Fraenkel E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Voet T; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, Belgium.; KU Leuven Institute for Single Cell Omics (LISCO), University of Leuven, KU Leuven, Leuven, Belgium., Enard W; Anthropology and Human Genomics, Faculty of Biology, Ludwig-Maximilians Universität München, 82152 Planegg, Germany., Carninci P; Laboratory for Transcriptome Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan.; Human Technopole, Milano, Italy., Heyn H; University of Barcelona (UB), Barcelona, Spain.; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain.; ICREA, Barcelona, Spain., Levin JZ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Mereu E; Josep Carreras Leukemia Research Institute, Barcelona, Spain.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 06. Date of Electronic Publication: 2025 Mar 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.03.06.637075