Sitagliptin attenuates L-dopa-induced dyskinesia by regulating mitochondrial proteins and neuronal activity in a 6-OHDA-induced mouse model of Parkinson's disease.

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Title: Sitagliptin attenuates L-dopa-induced dyskinesia by regulating mitochondrial proteins and neuronal activity in a 6-OHDA-induced mouse model of Parkinson's disease.
Authors: Park HY; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Ryu YK; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Lee GS; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk, 28160, Republic of Korea., Go J; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Kim JE; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Min KS; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.; Department of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, 50463, Korea., Lee CH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.; KRIBB School, University of Science and Technology, Daejeon, 34141, Republic of Korea., Moon JH; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. jhdal@kribb.re.kr., Kim KS; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125, Gwahak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea. kskim@kribb.re.kr.; KRIBB School, University of Science and Technology, Daejeon, 34141, Republic of Korea. kskim@kribb.re.kr.
Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2025 Jun; Vol. 132 (6), pp. 827-843. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1463 (Electronic) Linking ISSN: 03009564 NLM ISO Abbreviation: J Neural Transm (Vienna) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1435-1463
DOI:10.1007/s00702-025-02907-1