Electrophysiological Abnormalities and Pharmacological Corrections of Pathogenic Missense Variants in KCNQ3.

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Title: Electrophysiological Abnormalities and Pharmacological Corrections of Pathogenic Missense Variants in KCNQ3.
Authors: Wu X; School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, 550025, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China., Gong J; School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, 550025, China.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China., Qiu L; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China., Yang G; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China., Yuan H; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China., Shen X; School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, 550025, China., Shen Y; Translational Research Center for the Nervous System, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, Guangdong, China. lindia10597@163.com.; Faculty of Pediatrics, Chinese PLA General Hospital, Graduate School of the PLA General Hospital, Beijing, 100853, China. lindia10597@163.com., Tian F; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. tianfuyun@zidd.ac.cn., Gao Z; School of Pharmaceutical Sciences, Guizhou Medical University, Guiyang, 550025, China. zbgao@simm.ac.cn.; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. zbgao@simm.ac.cn.; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China. zbgao@simm.ac.cn.
Source: Neuroscience bulletin [Neurosci Bull] 2025 Sep; Vol. 41 (9), pp. 1511-1521. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 101256850 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1995-8218 (Electronic) Linking ISSN: 19958218 NLM ISO Abbreviation: Neurosci Bull Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1995-8218
DOI:10.1007/s12264-025-01378-4