IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia.

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Title: IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia.
Authors: Horn S; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Schmid M; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Berest I; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Piattini F; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Zhang J; Department of Health Sciences and Technology, Laboratory of Exercise and Health, ETH Zurich, Zurich, Switzerland., de Bock K; Department of Health Sciences and Technology, Laboratory of Exercise and Health, ETH Zurich, Zurich, Switzerland., Devuyst O; Institute of Physiology, University of Zurich, Zurich, Switzerland., Nlandu Khodo S; Institute of Physiology, University of Zurich, Zurich, Switzerland., Kisielow J; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Kopf M; Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland. manfred.kopf@ethz.ch.
Source: Nature communications [Nat Commun] 2025 Mar 17; Vol. 16 (1), pp. 2626. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57797-4