Enhancing therapeutic efficacy through degradation of endogenous extracellular matrix in primary breast tumor spheroids.

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Title: Enhancing therapeutic efficacy through degradation of endogenous extracellular matrix in primary breast tumor spheroids.
Authors: Lo Cicero A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Italy., Campora S; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Italy.; Department of Biomedical Engineering Bioscience Center of the University of Cincinnati, OH, USA., Lo Buglio G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Italy.; Department of Pharmacy, University of Copenhagen, Denmark., Cinà P; Abiel Srl, Palermo, Italy., Lo Pinto M; Proteomics Group of Ri.MED Foundation, Research Department IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy., Scilabra SD; Proteomics Group of Ri.MED Foundation, Research Department IRCCS ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione), Palermo, Italy., Ghersi G; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Italy.; Abiel Srl, Palermo, Italy.
Source: The FEBS journal [FEBS J] 2025 Jul; Vol. 292 (13), pp. 3494-3507. Date of Electronic Publication: 2025 Mar 17.
Publication Type: Journal Article
Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1742-4658
DOI:10.1111/febs.70069