Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma.
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| Title: | Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma. |
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| Authors: | Ramchatesingh B; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Martinez Villarreal A; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Lefrançois P; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada.; Division of Dermatology, McGill University Health Center, Montreal, Canada.; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University Montreal, Canada., Gantchev J; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Sivachandran S; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Abou Setah S; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada., Litvinov IV; Division of Experimental Medicine, McGill University, Montreal, Canada.; Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada.; Division of Dermatology, McGill University Health Center, Montreal, Canada. |
| Source: | Molecular oncology [Mol Oncol] 2025 May; Vol. 19 (5), pp. 1471-1492. Date of Electronic Publication: 2025 Mar 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1878-0261 |
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| DOI: | 10.1002/1878-0261.13820 |
