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TIE-2-Expressing Monocytic Myeloid-Derived Suppressor Cells Are Involved in Resistance to Anti-PD-1 Therapy Mediated by Angiopoietin 2 in Patients with Melanoma.

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Title: TIE-2-Expressing Monocytic Myeloid-Derived Suppressor Cells Are Involved in Resistance to Anti-PD-1 Therapy Mediated by Angiopoietin 2 in Patients with Melanoma.
Authors: Marguier A; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Mathiot J; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., NDao B; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Wespiser M; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France; Department of Oncology, University Hospital of Besançon, Besançon, France., Pereira V; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France; Department of Pediatry, University Hospital of Besançon, Besançon, France., Lecoester B; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Boullerot L; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Malfroy M; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Laheurte C; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France., Aubin F; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France; Department of Dermatology, University Hospital of Besançon, Besançon, France., Adotevi O; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France; Department of Oncology, University Hospital of Besançon, Besançon, France., Nardin C; EFS, INSERM, UMR RIGHT, Université Marie et Louis Pasteur, Besançon, France; Department of Dermatology, University Hospital of Besançon, Besançon, France. Electronic address: cnardin@chu-besancon.fr.
Source: The Journal of investigative dermatology [J Invest Dermatol] 2025 Oct; Vol. 145 (10), pp. 2636-2640.e3. Date of Electronic Publication: 2025 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1523-1747
DOI:10.1016/j.jid.2025.02.150