Genetics and clinical implications of SPINK1 in the pancreatitis continuum and pancreatic cancer.

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Title: Genetics and clinical implications of SPINK1 in the pancreatitis continuum and pancreatic cancer.
Authors: Wang QW; Department of Gastroenterology, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.; Shanghai Institute of Pancreatic Diseases, Shanghai, China., Zou WB; Department of Gastroenterology, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, 168 Changhai Road, Shanghai, 200433, China.; Shanghai Institute of Pancreatic Diseases, Shanghai, China., Masson E; Univ Brest, Inserm, EFS, UMR 1078, GGB, 29200, Brest, France.; Service de Génétique Médicale et de Biologie de la Reproduction, CHU Brest, Brest, France., Férec C; Univ Brest, Inserm, EFS, UMR 1078, GGB, 29200, Brest, France., Liao Z; Department of Gastroenterology, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, 168 Changhai Road, Shanghai, 200433, China. liaozhuan@smmu.edu.cn.; Shanghai Institute of Pancreatic Diseases, Shanghai, China. liaozhuan@smmu.edu.cn., Chen JM; Univ Brest, Inserm, EFS, UMR 1078, GGB, 29200, Brest, France. jian-min.chen@univ-brest.fr.; Univ Brest, Inserm, EFS, UMR 1078, GGB, 22 Avenue Camille Desmoulins, 29238, Brest, France. jian-min.chen@univ-brest.fr.
Source: Human genomics [Hum Genomics] 2025 Mar 26; Vol. 19 (1), pp. 32. Date of Electronic Publication: 2025 Mar 26.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101202210 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-7364 (Electronic) Linking ISSN: 14739542 NLM ISO Abbreviation: Hum Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1479-7364
DOI:10.1186/s40246-025-00740-x