Deciphering lung adenocarcinoma evolution and the role of LINE-1 retrotransposition.

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Title: Deciphering lung adenocarcinoma evolution and the role of LINE-1 retrotransposition.
Authors: Zhang T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Zhao W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Wirth C; Manchester Cancer Research Centre, The University of Manchester, Manchester, UK., Díaz-Gay M; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.; Digital Genomics Group, Structural Biology Program, Spanish National Cancer Research Center (CNIO), Madrid, Spain., Yin J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Cecati M; Advanced Technology Center for Aging Research, IRCCS INRCA, Ancona, Italy., Marchegiani F; Clinic of Laboratory and Precision Medicine, IRCCS INRCA, Ancona, Italy., Hoang PH; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Leduc C; Department of Pathology, Centre Hospitalier de l'Université de Montréal, Montreal, Canada., Baine MK; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Travis WD; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Joubert P; Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Canada., Sang J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., McElderry JP; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Klein A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Khandekar A; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA., Hartman C; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Rosenbaum J; Westat, Rockville, MD, USA., Colón-Matos FJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Miraftab M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Saha M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Lee OW; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Jones KM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Caporaso NE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Wong MP; Queen Mary Hospital, The University of Hong Kong, Hong Kong, China., Leung KC; Department of Pathology, The University of Hong Kong, Hong Kong, China., Agnes Hsiung C; Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan., Chen CY; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Surgery, Division of Thoracic Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan., Edell ES; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA., Martínez Santamaría J; Biobanco IBSP-CV FISABIO, Valencia, Spain.; Red Valenciana de Biobancos FISABIO, Valencia, Spain., Schabath MB; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., Yendamuri SS; Thoracic Surgery, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA., Manczuk M; Department of Cancer Epidemiology and Primary Prevention, Maria Skłodowska-Curie National Research Institute of Oncology, Warshaw, Poland., Lissowska J; Department of Cancer Epidemiology and Primary Prevention, Maria Skłodowska-Curie National Research Institute of Oncology, Warshaw, Poland., Świątkowska B; Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland., Mukeria A; Department of Clinical Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia., Shangina O; Department of Clinical Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia., Zaridze D; Department of Clinical Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia., Holcatova I; Institute of Hygiene and Epidemiology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.; Department of Oncology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic., Mates D; Department of Occupational Health and Toxicology, National Center for Environmental Risk Monitoring, National Institute of Public Health, Bucharest, Romania., Milosavljevic S; International Organisation for Cancer Prevention and Research (IOCPR), Belgrade, Serbia., Savic M; Department of Thoracic Surgery, Clinical Center of Serbia, Belgrade, Serbia., Bossé Y; Institut universitaire de cardiologie et de pneumologie de Québec, Laval University, Quebec City, Canada., Gould Rothberg BE; Sylvester Comprehensive Cancer Center, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA., Christiani DC; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Gaborieau V; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Brennan P; Genomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France., Liu G; Princess Margaret Cancer Center, University of Toronto, Toronto, Ontario, Canada., Hofman P; IHU RespirERA, Biobank-BB-0033-0025, Côte d'Azur University, Nice, France., Homer R; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Yang SR; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pesatori AC; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Consonni D; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Yang L; Ben May Department for Cancer Research, The University of Chicago, Chicago, IL, USA.; Department of Human Genetics, The University of Chicago, Chicago, IL, USA.; The University of Chicago Medicine Comprehensive Cancer Center, The University of Chicago, Chicago, IL, USA., Zhu B; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Brown K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Alexandrov LB; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.; Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA, USA., Choi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Cardelli M; Advanced Technology Center for Aging Research, IRCCS INRCA, Ancona, Italy., Lan Q; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Nowak MA; Department of Mathematics, Harvard University, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Wedge DC; Manchester Cancer Research Centre, The University of Manchester, Manchester, UK.; Manchester NIHR Biomedical Research Centre, Manchester, UK., Landi MT; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Mar 16. Date of Electronic Publication: 2025 Mar 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.03.14.643063