Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load.
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| Title: | Neurological disability and brain grey matter atrophy in primary progressive multiple sclerosis are determined by microstructural lesional changes, but not by lesion load. |
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| Authors: | Ladopoulos T; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany. Theodoros.Ladopoulos@rub.de.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany. Theodoros.Ladopoulos@rub.de., Abbas Z; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Krieger B; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., Bellenberg B; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., James JC; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Bauer J; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Gold R; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany., Lukas C; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany., Schneider R; Department of Neurology, St Josef Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.; Institute of Neuroradiology, St Josef Hospital, Ruhr University, Bochum, Germany. |
| Source: | Journal of neurology [J Neurol] 2025 Apr 01; Vol. 272 (4), pp. 302. Date of Electronic Publication: 2025 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1459 |
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| DOI: | 10.1007/s00415-025-13043-x |
