Periurethral versus intravaginal application of vaginal estrogen for the prevention of urinary tract infections in postmenopausal women: Design of a randomized non-inferiority trial.

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Title: Periurethral versus intravaginal application of vaginal estrogen for the prevention of urinary tract infections in postmenopausal women: Design of a randomized non-inferiority trial.
Authors: Zuo SW; Department of Obstetrics and Gynecology, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, VA 22903, United States of America; Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, United States of America. Electronic address: stephanie.zuo@uvahealth.org., Bradley M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, United States of America; University of Pittsburgh and Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, United States of America., Mowers EE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, United States of America., Zyczynski HM; Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, United States of America; University of Pittsburgh and Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, United States of America., Hillier SL; University of Pittsburgh and Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, United States of America., Ackenbom MF; Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, United States of America; University of Pittsburgh and Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA 15213, United States of America.
Source: Contemporary clinical trials [Contemp Clin Trials] 2025 Jun; Vol. 153, pp. 107893. Date of Electronic Publication: 2025 Mar 30.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101242342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-2030 (Electronic) Linking ISSN: 15517144 NLM ISO Abbreviation: Contemp Clin Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1559-2030
DOI:10.1016/j.cct.2025.107893