Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail.
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| Title: | Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail. |
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| Authors: | Breault É; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12è avenue nord, Sherbrooke, QC, J1H5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada., Brouillette RL; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12è avenue nord, Sherbrooke, QC, J1H5N4, Canada.; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada., Hébert TE; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada., Sarret P; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12è avenue nord, Sherbrooke, QC, J1H5N4, Canada. philippe.sarret@usherbrooke.ca.; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada. philippe.sarret@usherbrooke.ca.; RECITAL International Partnership Lab, Université de Caen-Normandie & Université de Sherbrooke, Caen, France. philippe.sarret@usherbrooke.ca., Besserer-Offroy É; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12è avenue nord, Sherbrooke, QC, J1H5N4, Canada. elie.besserer-offroy@inserm.fr.; RECITAL International Partnership Lab, Université de Caen-Normandie & Université de Sherbrooke, Caen, France. elie.besserer-offroy@inserm.fr.; Université de Caen Normandie, INSERM U1086 - Anticipe, 3 avenue général Harris, BP 45026, 14076, Caen Cedex 5, France. elie.besserer-offroy@inserm.fr.; Baclesse Comprehensive Cancer Center, UNICANCER, Caen, France. elie.besserer-offroy@inserm.fr. |
| Source: | CNS drugs [CNS Drugs] 2025 Jun; Vol. 39 (6), pp. 565-581. Date of Electronic Publication: 2025 Apr 01. |
| Publication Type: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1934 (Electronic) Linking ISSN: 11727047 NLM ISO Abbreviation: CNS Drugs Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1179-1934 |
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| DOI: | 10.1007/s40263-025-01172-w |
