Durable response to Olaparib in EGFR and somatic BRCA2-mutated lung adenocarcinoma with leptomeningeal metastases: a case report.

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Title: Durable response to Olaparib in EGFR and somatic BRCA2-mutated lung adenocarcinoma with leptomeningeal metastases: a case report.
Authors: Hou FF; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Liu LR; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Zhao WJ; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China., Qu YC; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Zhou R; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Wang TL; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China., Ye YS; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Chai XS; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China., Zhang HB; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China.; Department of Oncology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China.; Guangdong-Hong Kong-Macau Joint Laboratory on Chinese Medicine and Immune Disease Research, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.; Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Source: Frontiers in oncology [Front Oncol] 2025 Mar 20; Vol. 15, pp. 1512886. Date of Electronic Publication: 2025 Mar 20 (Print Publication: 2025).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2234-943X
DOI:10.3389/fonc.2025.1512886