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The Estonian Biobank's journey from biobanking to personalized medicine.

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Title: The Estonian Biobank's journey from biobanking to personalized medicine.
Authors: Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. lili.milani@ut.ee.; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia. lili.milani@ut.ee., Alver M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Laur S; Institute of Computer Science, University of Tartu, Tartu, Estonia.; STACC, Tartu, Estonia., Reisberg S; Institute of Computer Science, University of Tartu, Tartu, Estonia.; STACC, Tartu, Estonia., Haller T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Aasmets O; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Abner E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Alavere H; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Allik A; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Annilo T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Fischer K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Hofmeister R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland., Hudjashov G; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia., Jõeloo M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kals M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Karo-Astover L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kasela S; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kolde A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Krebs K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Krigul KL; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kronberg J; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kruusmaa K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kukuškina V; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kõiv K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lehto K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Leitsalu L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lind S; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Luitva LB; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia., Läll K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lüll K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Metsalu K; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu M; Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mõttus R; Institute of Psychology, University of Tartu, Tartu, Estonia.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Nelis M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Nikopensius T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Nurm M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Nõukas M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Oja M; Institute of Computer Science, University of Tartu, Tartu, Estonia., Org E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Palover M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Palta P; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Pankratov V; Centre for Genomics, Evolution and Medicine, Institute of Genomics, University of Tartu, Tartu, Estonia., Pantiukh K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Pervjakova N; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Pujol-Gualdo N; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reigo A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reimann E; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Smit S; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Rogozina D; Estonian Biobank, Institute of Genomics, University of Tartu, Tartu, Estonia., Särg D; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Taba N; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Talvik HA; Institute of Computer Science, University of Tartu, Tartu, Estonia.; STACC, Tartu, Estonia., Teder-Laving M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Tõnisson N; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Vaht M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Vainik U; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Institute of Psychology, University of Tartu, Tartu, Estonia.; Montreal Neurological Institute, McGill University, Montreal, Canada., Võsa U; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Yelmen B; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Kolde R; Institute of Computer Science, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Vilo J; Institute of Computer Science, University of Tartu, Tartu, Estonia.; STACC, Tartu, Estonia., Laisk T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. andres.metspalu@ut.ee.
Source: Nature communications [Nat Commun] 2025 Apr 05; Vol. 16 (1), pp. 3270. Date of Electronic Publication: 2025 Apr 05.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-58465-3