A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide.
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| Title: | A naturally selected αβ T cell receptor binds HLA-DQ2 molecules without co-contacting the presented peptide. |
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| Authors: | Lim JJ; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Jones CM; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Loh TJ; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Dao HT; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Tran MT; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Tye-Din JA; Immunology Division, The Walter and Eliza Hall Institute, Parkville, VIC, Australia., La Gruta NL; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia. nicole.la.gruta@monash.edu., Rossjohn J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia. jamie.rossjohn@monash.edu.; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK. jamie.rossjohn@monash.edu. |
| Source: | Nature communications [Nat Commun] 2025 Apr 08; Vol. 16 (1), pp. 3330. Date of Electronic Publication: 2025 Apr 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-58690-w |