Early-life gut microbiome associates with positive vaccine take and shedding in neonatal schedule of the human neonatal rotavirus vaccine RV3-BB.
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| Title: | Early-life gut microbiome associates with positive vaccine take and shedding in neonatal schedule of the human neonatal rotavirus vaccine RV3-BB. |
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| Authors: | Wagner J; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia. josef.wagner@mcri.edu.au.; Respiratory Virus and Microbiome Initiative, Wellcome Sanger Institute, Hinxton, UK. josef.wagner@mcri.edu.au.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. josef.wagner@mcri.edu.au., Handley A; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Medicines Development for Global Health, Melbourne, Victoria, Australia., Donato CM; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia., Lyons EA; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Pavlic D; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Ong DS; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Bonnici R; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Bogdanovic-Sakran N; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Parker EPK; Department of Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine, London, UK., Bronowski C; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Thobari JA; Department of Pharmacology and Therapy, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia.; Pediatric Research Office, Department of Pediatrics, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia., Satria CD; Pediatric Research Office, Department of Pediatrics, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia., Nirwati H; Department of Microbiology, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia., Witte D; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Malawi Liverpool Wellcome Programme, Blantyre, P.O. Box 30096, Chichiri, Malawi., Jere KC; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; Malawi Liverpool Wellcome Programme, Blantyre, P.O. Box 30096, Chichiri, Malawi., Mpakiza A; Malawi Liverpool Wellcome Programme, Blantyre, P.O. Box 30096, Chichiri, Malawi., Watts E; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Turner A; Malawi Liverpool Wellcome Programme, Blantyre, P.O. Box 30096, Chichiri, Malawi., Boniface K; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Mandolo J; Malawi Liverpool Wellcome Programme, Blantyre, P.O. Box 30096, Chichiri, Malawi.; Department of Clinical Science, Liverpool School of Tropical Medicine, Liverpool, UK., Justice F; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia., Bar-Zeev N; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Iturriza-Gomara M; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.; GSK Vaccines for Global Health Institute, Sienna, Italy., Buttery JP; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.; Department of Infectious Diseases, Royal Children's Hospital, Parkville, Australia., Cunliffe NA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Soenarto Y; Pediatric Research Office, Department of Pediatrics, Faculty of Medicine, Nursing and Universitas Gadjah Mada, Yogyakarta, Indonesia., Bines JE; Enteric Diseases, Murdoch Children's Research Institute, Parkville, Victoria, Australia. jebines@unimelb.edu.au.; Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia. jebines@unimelb.edu.au.; Department of Gastroenterology and Clinical Nutrition, Royal Children's Hospital, Parkville, Australia. jebines@unimelb.edu.au. |
| Source: | Nature communications [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3432. Date of Electronic Publication: 2025 Apr 11. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-58632-6 |
