Cerebral hypoperfusion, brain structural integrity, and cognitive impairment in older APOE4 carriers.
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| Title: | Cerebral hypoperfusion, brain structural integrity, and cognitive impairment in older APOE4 carriers. |
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| Authors: | Pappas I; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Lohman T; Leonard Davis School of Gerontology, University of Southern California, Andrus Gerontology Center, 3715 McClintock Ave, Los Angeles, CA, 90089, USA., Dutt S; Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA., Kapoor A; Department of Psychological Science, University of California, Irvine, Irvine, CA, USA., Engstrom AC; Department of Psychological Science, University of California, Irvine, Irvine, CA, USA., Alitin JPM; Leonard Davis School of Gerontology, University of Southern California, Andrus Gerontology Center, 3715 McClintock Ave, Los Angeles, CA, 90089, USA., Barnes S; Department of Radiology, Loma Linda University, Loma Linda, CA, USA., Chakhoyan A; Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Saca L; Department of Radiology, Loma Linda University, Loma Linda, CA, USA., Gaggar R; Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Nourollahimoghadam E; Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Wang DJJ; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Lai MHC; Deparment of Psychology, Dana and David Dornsife College of Arts and Letters, University of Southern California, Los Angeles, CA, USA., Joe EB; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Ringman JM; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Yassine HN; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Schneider LS; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of Southern California, Los Angeles, CA, USA., Chui HC; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Toga AW; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Zlokovic BV; Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Nation DA; Leonard Davis School of Gerontology, University of Southern California, Andrus Gerontology Center, 3715 McClintock Ave, Los Angeles, CA, 90089, USA. danation@usc.edu.; Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. danation@usc.edu.; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. danation@usc.edu.; Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. danation@usc.edu. |
| Source: | GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 4973-4986. Date of Electronic Publication: 2025 Apr 12. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2509-2723 |
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| DOI: | 10.1007/s11357-025-01642-5 |
