High-dose hydroxychloroquine induces changes in low-frequency brain oscillations in electrocorticographic records not concurrent with alterations in cardiac, hepatic, and renal function in wistar rats.

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Title: High-dose hydroxychloroquine induces changes in low-frequency brain oscillations in electrocorticographic records not concurrent with alterations in cardiac, hepatic, and renal function in wistar rats.
Authors: de Souza CEM; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil., de Araújo DB; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: danivivaf@gmail.com., Santos RNO; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Amoras LHB; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., de Campos ALC; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., da Paz CA; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., de Sousa Reis T; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Eiró-Quirino L; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., da Silva LGS; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Noronha MH; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Hamoy MKO; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Gomes DL; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil., Hamoy M; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: hamoyufpa@gmail.com.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 May; Vol. 186, pp. 117980. Date of Electronic Publication: 2025 Apr 12.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1950-6007
DOI:10.1016/j.biopha.2025.117980