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High-dose hydroxychloroquine induces changes in low-frequency brain oscillations in electrocorticographic records not concurrent with alterations in cardiac, hepatic, and renal function in wistar rats.

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Title: High-dose hydroxychloroquine induces changes in low-frequency brain oscillations in electrocorticographic records not concurrent with alterations in cardiac, hepatic, and renal function in wistar rats.
Authors: de Souza CEM; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil., de Araújo DB; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: danivivaf@gmail.com., Santos RNO; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Amoras LHB; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., de Campos ALC; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., da Paz CA; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., de Sousa Reis T; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Eiró-Quirino L; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., da Silva LGS; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Noronha MH; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Hamoy MKO; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil., Gomes DL; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil., Hamoy M; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: hamoyufpa@gmail.com.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 May; Vol. 186, pp. 117980. Date of Electronic Publication: 2025 Apr 12.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-dose hydroxychloroquine induces changes in low-frequency brain oscillations in electrocorticographic records not concurrent with alterations in cardiac, hepatic, and renal function in wistar rats.
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  Data: <searchLink fieldCode="AU" term="%22de+Souza+CEM%22">de Souza CEM</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Araújo+DB%22">de Araújo DB</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: danivivaf@gmail.com.<br /><searchLink fieldCode="AU" term="%22Santos+RNO%22">Santos RNO</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Amoras+LHB%22">Amoras LHB</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Campos+ALC%22">de Campos ALC</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Paz+CA%22">da Paz CA</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Sousa+Reis+T%22">de Sousa Reis T</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Eiró-Quirino+L%22">Eiró-Quirino L</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+LGS%22">da Silva LGS</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Noronha+MH%22">Noronha MH</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Hamoy+MKO%22">Hamoy MKO</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Gomes+DL%22">Gomes DL</searchLink>; Behavior Theory and Research Center, Federal University of Para, Para, Belem, Brazil.<br /><searchLink fieldCode="AU" term="%22Hamoy+M%22">Hamoy M</searchLink>; Laboratory of Pharmacology and Toxicology of Natural Products, Biological Sciences Institute, Federal University of Para, Para, Belem, Brazil. Electronic address: hamoyufpa@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2025 May; Vol. 186, pp. 117980. <i>Date of Electronic Publication: </i>2025 Apr 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE
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              Text: 2025 May
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