Single-Cell Transcriptional Analysis Reveals the Mechanism of AZD6738 in HCC Immunotherapy via EZH2 Targeting.

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Title: Single-Cell Transcriptional Analysis Reveals the Mechanism of AZD6738 in HCC Immunotherapy via EZH2 Targeting.
Authors: Li RP; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Wu GZ; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Fang XD; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Yang WW; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Zhang HY; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Yue HX; The First Clinical Medical College, Lanzhou University, Lanzhou, People's Republic of China.; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Zheng Y; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Wang YP; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China., Zhou YN; Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.; Gansu Province Clinical Research Center for Digestive Diseases, The First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2025 Apr 14; Vol. 19, pp. 2897-2920. Date of Electronic Publication: 2025 Apr 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1177-8881
DOI:10.2147/DDDT.S508709