Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study.
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| Title: | Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study. |
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| Authors: | De Matteis E; Department of Brain Sciences, Imperial College London, London, UK., De Santis F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Foschi M; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Romoli M; Department of Neuroscience, Maurizio Bufalini Hospital, AUSL Romagna, Cesena, Italy., Tassinari T; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy., Saia V; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy., Cenciarelli S; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Bedetti C; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Padiglioni C; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Censori B; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Puglisi V; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Vinciguerra L; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Guarino M; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Barone V; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Zedde M; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Grisendi I; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Maestrini I; Stroke Center, Tor Vergata University Hospital, Rome, Italy., Bagnato MR; Stroke Center, Tor Vergata University Hospital, Rome, Italy., Petruzzellis M; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy., Mezzapesa DM; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy., Di Viesti P; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy., Inchingolo V; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy., Cappellari M; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Zenorini M; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Candelaresi P; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy., Andreone V; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy., Rinaldi G; Department of Neurology, Di Venere Hospital, Bari, Italy., Bavaro A; Department of Neurology, Di Venere Hospital, Bari, Italy., Cavallini A; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy., Moraru S; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy., Piscaglia MG; Department of Neuroscience, S. Maria Delle Croci Hospital, AUSL Romagna, Ravenna, Italy., Terruso V; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy., Mannino M; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy., Pezzini A; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Stroke Care Program, Department of Emergency, Parma University Hospital, Parma, Italy., Frisullo G; Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy., Muscia F; Department of Neurology, ASST-Ovest Milanese, Legnano, Italy., Paciaroni M; Department of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy., Mosconi MG; Stroke Unit, Department of Internal and Cardiovascular Medicine, University Hospital Santa Maria Della Misericordia, Perugia, Italy., Zini A; Department of Neurology and Stroke Center, Maggiore Hospital, IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Leone R; Department of Neurology and Stroke Unit, 'M. R. Dimiccoli' General Hospital, Barletta, Italy., Palmieri C; Stroke Unit, Department of Neurology, E. Agnelli Hospital, Pinerolo, Italy., Cupini LM; Stroke Unit, Department of Neurology, S. Eugenio Hospital, Rome, Italy., Marcon M; Department of Neurology, Cazzavillan Hospital Arzignano, Vicenza, Italy., Tassi R; Urgency and Emergency Department, Azienda Ospedaliera Universitaria Senese, Siena, Italy., Sanzaro E; Department of Neurology, Umberto I Hospital, Siracusa, Italy., Paci C; UOC Neurologia, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, Italy., Viticchi G; Experimental and Clinical Medicine Department, Marche Polytechnic University, Ancona, Italy., Orsucci D; Unit of Neurology-San Luca Hospital, Lucca and Castelnuovo Garfagnana, Italy., Falcou A; Stroke Unit, Emergency Department, Policlinico Umberto I Hospital, Rome, Italy., Diamanti S; Department of Neurology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Tarletti R; Stroke Unit, SCDU Neurologia, Azienda Ospedaliero-Universitaria 'Maggiore Della Carità', Novara, Italy., Nencini P; Stroke Unit, Careggi University Hospital, Florence, Italy., Rota E; Department of Neurology, San Giacomo Hospital, Novi Ligure, Italy., Sepe FN; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy., Ferrandi D; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy., Caputi L; Department of Cardiocerebrovascular Diseases, Neurology-Stroke Unit-ASST Ospedale Maggiore di Crema, Crema, Italy., Volpi G; Department of Neurology, San Jacopo Hospital, Pistoia, Italy., La Spada S; Department of Neurology, Antonio Perrino Hospital, Brindisi, Italy., Beccia M; Department of Neurology, Sant'andrea Hospital, Rome, Italy., Rinaldi C; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy., Mastrangelo V; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy., Di Blasio F; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy., Invernizzi P; Departiment of Neurology, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy., Pelliccioni G; Department of Neurology, INRCA, Ancona, Italy., De Angelis MV; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy.; Stroke Unit, Department of Neurology, SS Annunziata Hospital, Chieti, Italy., Bonanni L; Dipartimento di Medicina e Scienze Dell'Invecchiamento, Università G. D'Annunzio di Chieti-Pescara, E Clinica Neurologica e Stroke Unit Ospedale Clinicizzato SS. Annunziata di Chieti, Chieti, Italy., Ruzza G; Department of Neurology, Civil Hospital, Cittadella, Italy., Caggia EA; Neurology Unit, Cardio-Neuro-Vascular Department, Giovanni Paolo II Hospital, Ragusa, Italy., Russo M; Department of Neurology, St Misericordia Hospital, Rovigo, Italy., Tonon A; Department of Neurology, Ospedale Civile SS. Giovanni e Paolo, Venice, Italy., Acciarri MC; Department of Neurology, A. Murri Fermo Hospital, Fermo, Italy., Anticoli S; Stroke Unit, Azienda Ospedaliera San Camillo, Rome, Italy., Roberti C; Department of Neurology, San Filippo Neri Hospital, Rome, Italy., Manobianca G; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy., Scaglione G; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy., Pistoia F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Fortini A; Internal Medicine, San Giovanni di Dio Hospital, Florence, Italy., De Boni A; Department of Neuroscience, San Bortolo Hospital, Vicenza, Italy., Sanna A; Stroke Unit, AOU Sassari, Sassari, Italy., Chiti A; Unit of Neurology, Apuane Hospital, Massa, Italy., Barbarini L; Department of Neurology, Vito Fazi Hospital, Lecce, Italy., Caggiula M; Department of Neurology, Vito Fazi Hospital, Lecce, Italy., Masato M; Department of Neurology, Mirano Hospital, Mirano, Italy., Del Sette M; Department of Neuroscience, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Passarelli F; Department of Neurology, Fatebenefratelli Hospital, Rome, Italy., Bongioanni MR; Department of Neurology, SS Annunziata Hospital, Savigliano, Italy., Toni D; Department of Human Neurosciences, University of Rome La Sapienza, Rome, Italy., Ricci S; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.; Coordinatore Comitato Scientifico ISA-AII, Italy., Sacco S; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Ornello R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. |
| Corporate Authors: | READAPT Study Group |
| Source: | European journal of neurology [Eur J Neurol] 2025 Apr; Vol. 32 (4), pp. e70163. |
| Publication Type: | Journal Article; Observational Study; Multicenter Study |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1468-1331 |
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| DOI: | 10.1111/ene.70163 |
