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Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study.

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Title: Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study.
Authors: De Matteis E; Department of Brain Sciences, Imperial College London, London, UK., De Santis F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Foschi M; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Romoli M; Department of Neuroscience, Maurizio Bufalini Hospital, AUSL Romagna, Cesena, Italy., Tassinari T; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy., Saia V; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy., Cenciarelli S; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Bedetti C; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Padiglioni C; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy., Censori B; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Puglisi V; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Vinciguerra L; Department of Neurology, ASST Crema Hospital, Cremona, Italy., Guarino M; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Barone V; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Zedde M; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Grisendi I; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy., Maestrini I; Stroke Center, Tor Vergata University Hospital, Rome, Italy., Bagnato MR; Stroke Center, Tor Vergata University Hospital, Rome, Italy., Petruzzellis M; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy., Mezzapesa DM; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy., Di Viesti P; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy., Inchingolo V; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy., Cappellari M; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Zenorini M; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy., Candelaresi P; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy., Andreone V; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy., Rinaldi G; Department of Neurology, Di Venere Hospital, Bari, Italy., Bavaro A; Department of Neurology, Di Venere Hospital, Bari, Italy., Cavallini A; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy., Moraru S; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy., Piscaglia MG; Department of Neuroscience, S. Maria Delle Croci Hospital, AUSL Romagna, Ravenna, Italy., Terruso V; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy., Mannino M; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy., Pezzini A; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Stroke Care Program, Department of Emergency, Parma University Hospital, Parma, Italy., Frisullo G; Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy., Muscia F; Department of Neurology, ASST-Ovest Milanese, Legnano, Italy., Paciaroni M; Department of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy., Mosconi MG; Stroke Unit, Department of Internal and Cardiovascular Medicine, University Hospital Santa Maria Della Misericordia, Perugia, Italy., Zini A; Department of Neurology and Stroke Center, Maggiore Hospital, IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy., Leone R; Department of Neurology and Stroke Unit, 'M. R. Dimiccoli' General Hospital, Barletta, Italy., Palmieri C; Stroke Unit, Department of Neurology, E. Agnelli Hospital, Pinerolo, Italy., Cupini LM; Stroke Unit, Department of Neurology, S. Eugenio Hospital, Rome, Italy., Marcon M; Department of Neurology, Cazzavillan Hospital Arzignano, Vicenza, Italy., Tassi R; Urgency and Emergency Department, Azienda Ospedaliera Universitaria Senese, Siena, Italy., Sanzaro E; Department of Neurology, Umberto I Hospital, Siracusa, Italy., Paci C; UOC Neurologia, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, Italy., Viticchi G; Experimental and Clinical Medicine Department, Marche Polytechnic University, Ancona, Italy., Orsucci D; Unit of Neurology-San Luca Hospital, Lucca and Castelnuovo Garfagnana, Italy., Falcou A; Stroke Unit, Emergency Department, Policlinico Umberto I Hospital, Rome, Italy., Diamanti S; Department of Neurology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy., Tarletti R; Stroke Unit, SCDU Neurologia, Azienda Ospedaliero-Universitaria 'Maggiore Della Carità', Novara, Italy., Nencini P; Stroke Unit, Careggi University Hospital, Florence, Italy., Rota E; Department of Neurology, San Giacomo Hospital, Novi Ligure, Italy., Sepe FN; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy., Ferrandi D; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy., Caputi L; Department of Cardiocerebrovascular Diseases, Neurology-Stroke Unit-ASST Ospedale Maggiore di Crema, Crema, Italy., Volpi G; Department of Neurology, San Jacopo Hospital, Pistoia, Italy., La Spada S; Department of Neurology, Antonio Perrino Hospital, Brindisi, Italy., Beccia M; Department of Neurology, Sant'andrea Hospital, Rome, Italy., Rinaldi C; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy., Mastrangelo V; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy., Di Blasio F; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy., Invernizzi P; Departiment of Neurology, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy., Pelliccioni G; Department of Neurology, INRCA, Ancona, Italy., De Angelis MV; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy.; Stroke Unit, Department of Neurology, SS Annunziata Hospital, Chieti, Italy., Bonanni L; Dipartimento di Medicina e Scienze Dell'Invecchiamento, Università G. D'Annunzio di Chieti-Pescara, E Clinica Neurologica e Stroke Unit Ospedale Clinicizzato SS. Annunziata di Chieti, Chieti, Italy., Ruzza G; Department of Neurology, Civil Hospital, Cittadella, Italy., Caggia EA; Neurology Unit, Cardio-Neuro-Vascular Department, Giovanni Paolo II Hospital, Ragusa, Italy., Russo M; Department of Neurology, St Misericordia Hospital, Rovigo, Italy., Tonon A; Department of Neurology, Ospedale Civile SS. Giovanni e Paolo, Venice, Italy., Acciarri MC; Department of Neurology, A. Murri Fermo Hospital, Fermo, Italy., Anticoli S; Stroke Unit, Azienda Ospedaliera San Camillo, Rome, Italy., Roberti C; Department of Neurology, San Filippo Neri Hospital, Rome, Italy., Manobianca G; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy., Scaglione G; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy., Pistoia F; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Fortini A; Internal Medicine, San Giovanni di Dio Hospital, Florence, Italy., De Boni A; Department of Neuroscience, San Bortolo Hospital, Vicenza, Italy., Sanna A; Stroke Unit, AOU Sassari, Sassari, Italy., Chiti A; Unit of Neurology, Apuane Hospital, Massa, Italy., Barbarini L; Department of Neurology, Vito Fazi Hospital, Lecce, Italy., Caggiula M; Department of Neurology, Vito Fazi Hospital, Lecce, Italy., Masato M; Department of Neurology, Mirano Hospital, Mirano, Italy., Del Sette M; Department of Neuroscience, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Passarelli F; Department of Neurology, Fatebenefratelli Hospital, Rome, Italy., Bongioanni MR; Department of Neurology, SS Annunziata Hospital, Savigliano, Italy., Toni D; Department of Human Neurosciences, University of Rome La Sapienza, Rome, Italy., Ricci S; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.; Coordinatore Comitato Scientifico ISA-AII, Italy., Sacco S; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Ornello R; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Corporate Authors: READAPT Study Group
Source: European journal of neurology [Eur J Neurol] 2025 Apr; Vol. 32 (4), pp. e70163.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Label: Title
  Group: Ti
  Data: Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22De+Matteis+E%22">De Matteis E</searchLink>; Department of Brain Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22De+Santis+F%22">De Santis F</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Foschi+M%22">Foschi M</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Romoli+M%22">Romoli M</searchLink>; Department of Neuroscience, Maurizio Bufalini Hospital, AUSL Romagna, Cesena, Italy.<br /><searchLink fieldCode="AU" term="%22Tassinari+T%22">Tassinari T</searchLink>; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy.<br /><searchLink fieldCode="AU" term="%22Saia+V%22">Saia V</searchLink>; Department of Neurology, Santa Corona Hospital, Pietra Ligure, Italy.<br /><searchLink fieldCode="AU" term="%22Cenciarelli+S%22">Cenciarelli S</searchLink>; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.<br /><searchLink fieldCode="AU" term="%22Bedetti+C%22">Bedetti C</searchLink>; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.<br /><searchLink fieldCode="AU" term="%22Padiglioni+C%22">Padiglioni C</searchLink>; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.<br /><searchLink fieldCode="AU" term="%22Censori+B%22">Censori B</searchLink>; Department of Neurology, ASST Crema Hospital, Cremona, Italy.<br /><searchLink fieldCode="AU" term="%22Puglisi+V%22">Puglisi V</searchLink>; Department of Neurology, ASST Crema Hospital, Cremona, Italy.<br /><searchLink fieldCode="AU" term="%22Vinciguerra+L%22">Vinciguerra L</searchLink>; Department of Neurology, ASST Crema Hospital, Cremona, Italy.<br /><searchLink fieldCode="AU" term="%22Guarino+M%22">Guarino M</searchLink>; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Barone+V%22">Barone V</searchLink>; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Zedde+M%22">Zedde M</searchLink>; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Grisendi+I%22">Grisendi I</searchLink>; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Maestrini+I%22">Maestrini I</searchLink>; Stroke Center, Tor Vergata University Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bagnato+MR%22">Bagnato MR</searchLink>; Stroke Center, Tor Vergata University Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Petruzzellis+M%22">Petruzzellis M</searchLink>; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Mezzapesa+DM%22">Mezzapesa DM</searchLink>; Stroke Unit, Department of Neurology, 'F. Puca' AOU Consorziale Policlinico, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Viesti+P%22">Di Viesti P</searchLink>; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Inchingolo+V%22">Inchingolo V</searchLink>; Department of Neurology, Fondazione Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Cappellari+M%22">Cappellari M</searchLink>; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Zenorini+M%22">Zenorini M</searchLink>; Department of Neuroscience, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Candelaresi+P%22">Candelaresi P</searchLink>; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Andreone+V%22">Andreone V</searchLink>; Stroke Unit, Department of Neurology, AORN Antonio Cardarelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Rinaldi+G%22">Rinaldi G</searchLink>; Department of Neurology, Di Venere Hospital, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Bavaro+A%22">Bavaro A</searchLink>; Department of Neurology, Di Venere Hospital, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Cavallini+A%22">Cavallini A</searchLink>; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Moraru+S%22">Moraru S</searchLink>; UO Neurologia D'urgenza e Stroke Unit, IRCCS Mondino Foundation, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Piscaglia+MG%22">Piscaglia MG</searchLink>; Department of Neuroscience, S. Maria Delle Croci Hospital, AUSL Romagna, Ravenna, Italy.<br /><searchLink fieldCode="AU" term="%22Terruso+V%22">Terruso V</searchLink>; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Mannino+M%22">Mannino M</searchLink>; Department of Neurology, AOOR Villa Sofia-Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Pezzini+A%22">Pezzini A</searchLink>; Department of Medicine and Surgery, University of Parma, Parma, Italy.; Stroke Care Program, Department of Emergency, Parma University Hospital, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Frisullo+G%22">Frisullo G</searchLink>; Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Muscia+F%22">Muscia F</searchLink>; Department of Neurology, ASST-Ovest Milanese, Legnano, Italy.<br /><searchLink fieldCode="AU" term="%22Paciaroni+M%22">Paciaroni M</searchLink>; Department of Neurosciences and Rehabilitation, University of Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Mosconi+MG%22">Mosconi MG</searchLink>; Stroke Unit, Department of Internal and Cardiovascular Medicine, University Hospital Santa Maria Della Misericordia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Zini+A%22">Zini A</searchLink>; Department of Neurology and Stroke Center, Maggiore Hospital, IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Leone+R%22">Leone R</searchLink>; Department of Neurology and Stroke Unit, 'M. R. Dimiccoli' General Hospital, Barletta, Italy.<br /><searchLink fieldCode="AU" term="%22Palmieri+C%22">Palmieri C</searchLink>; Stroke Unit, Department of Neurology, E. Agnelli Hospital, Pinerolo, Italy.<br /><searchLink fieldCode="AU" term="%22Cupini+LM%22">Cupini LM</searchLink>; Stroke Unit, Department of Neurology, S. Eugenio Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Marcon+M%22">Marcon M</searchLink>; Department of Neurology, Cazzavillan Hospital Arzignano, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Tassi+R%22">Tassi R</searchLink>; Urgency and Emergency Department, Azienda Ospedaliera Universitaria Senese, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Sanzaro+E%22">Sanzaro E</searchLink>; Department of Neurology, Umberto I Hospital, Siracusa, Italy.<br /><searchLink fieldCode="AU" term="%22Paci+C%22">Paci C</searchLink>; UOC Neurologia, Ospedale 'Madonna del Soccorso', San Benedetto del Tronto, Italy.<br /><searchLink fieldCode="AU" term="%22Viticchi+G%22">Viticchi G</searchLink>; Experimental and Clinical Medicine Department, Marche Polytechnic University, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Orsucci+D%22">Orsucci D</searchLink>; Unit of Neurology-San Luca Hospital, Lucca and Castelnuovo Garfagnana, Italy.<br /><searchLink fieldCode="AU" term="%22Falcou+A%22">Falcou A</searchLink>; Stroke Unit, Emergency Department, Policlinico Umberto I Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Diamanti+S%22">Diamanti S</searchLink>; Department of Neurology, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Tarletti+R%22">Tarletti R</searchLink>; Stroke Unit, SCDU Neurologia, Azienda Ospedaliero-Universitaria 'Maggiore Della Carità', Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Nencini+P%22">Nencini P</searchLink>; Stroke Unit, Careggi University Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Rota+E%22">Rota E</searchLink>; Department of Neurology, San Giacomo Hospital, Novi Ligure, Italy.<br /><searchLink fieldCode="AU" term="%22Sepe+FN%22">Sepe FN</searchLink>; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrandi+D%22">Ferrandi D</searchLink>; Stroke Unit, Department of Neurology, SS. Biagio e Arrigo Hospital, Alessandria, Italy.<br /><searchLink fieldCode="AU" term="%22Caputi+L%22">Caputi L</searchLink>; Department of Cardiocerebrovascular Diseases, Neurology-Stroke Unit-ASST Ospedale Maggiore di Crema, Crema, Italy.<br /><searchLink fieldCode="AU" term="%22Volpi+G%22">Volpi G</searchLink>; Department of Neurology, San Jacopo Hospital, Pistoia, Italy.<br /><searchLink fieldCode="AU" term="%22La+Spada+S%22">La Spada S</searchLink>; Department of Neurology, Antonio Perrino Hospital, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22Beccia+M%22">Beccia M</searchLink>; Department of Neurology, Sant'andrea Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rinaldi+C%22">Rinaldi C</searchLink>; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy.<br /><searchLink fieldCode="AU" term="%22Mastrangelo+V%22">Mastrangelo V</searchLink>; Neurology Unit, 'Infermi' Hospital, AUSL Romagna, Rimini, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Blasio+F%22">Di Blasio F</searchLink>; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22Invernizzi+P%22">Invernizzi P</searchLink>; Departiment of Neurology, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Pelliccioni+G%22">Pelliccioni G</searchLink>; Department of Neurology, INRCA, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22De+Angelis+MV%22">De Angelis MV</searchLink>; Stroke Unit, 'S.Spirito' Hospital, Pescara, Italy.; Stroke Unit, Department of Neurology, SS Annunziata Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Bonanni+L%22">Bonanni L</searchLink>; Dipartimento di Medicina e Scienze Dell'Invecchiamento, Università G. D'Annunzio di Chieti-Pescara, E Clinica Neurologica e Stroke Unit Ospedale Clinicizzato SS. Annunziata di Chieti, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Ruzza+G%22">Ruzza G</searchLink>; Department of Neurology, Civil Hospital, Cittadella, Italy.<br /><searchLink fieldCode="AU" term="%22Caggia+EA%22">Caggia EA</searchLink>; Neurology Unit, Cardio-Neuro-Vascular Department, Giovanni Paolo II Hospital, Ragusa, Italy.<br /><searchLink fieldCode="AU" term="%22Russo+M%22">Russo M</searchLink>; Department of Neurology, St Misericordia Hospital, Rovigo, Italy.<br /><searchLink fieldCode="AU" term="%22Tonon+A%22">Tonon A</searchLink>; Department of Neurology, Ospedale Civile SS. Giovanni e Paolo, Venice, Italy.<br /><searchLink fieldCode="AU" term="%22Acciarri+MC%22">Acciarri MC</searchLink>; Department of Neurology, A. Murri Fermo Hospital, Fermo, Italy.<br /><searchLink fieldCode="AU" term="%22Anticoli+S%22">Anticoli S</searchLink>; Stroke Unit, Azienda Ospedaliera San Camillo, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Roberti+C%22">Roberti C</searchLink>; Department of Neurology, San Filippo Neri Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Manobianca+G%22">Manobianca G</searchLink>; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy.<br /><searchLink fieldCode="AU" term="%22Scaglione+G%22">Scaglione G</searchLink>; Department of Neurology, General Regional Hospital 'F. Miulli', Acquaviva Delle Fonti, Italy.<br /><searchLink fieldCode="AU" term="%22Pistoia+F%22">Pistoia F</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Fortini+A%22">Fortini A</searchLink>; Internal Medicine, San Giovanni di Dio Hospital, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22De+Boni+A%22">De Boni A</searchLink>; Department of Neuroscience, San Bortolo Hospital, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Sanna+A%22">Sanna A</searchLink>; Stroke Unit, AOU Sassari, Sassari, Italy.<br /><searchLink fieldCode="AU" term="%22Chiti+A%22">Chiti A</searchLink>; Unit of Neurology, Apuane Hospital, Massa, Italy.<br /><searchLink fieldCode="AU" term="%22Barbarini+L%22">Barbarini L</searchLink>; Department of Neurology, Vito Fazi Hospital, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Caggiula+M%22">Caggiula M</searchLink>; Department of Neurology, Vito Fazi Hospital, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Masato+M%22">Masato M</searchLink>; Department of Neurology, Mirano Hospital, Mirano, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Sette+M%22">Del Sette M</searchLink>; Department of Neuroscience, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Passarelli+F%22">Passarelli F</searchLink>; Department of Neurology, Fatebenefratelli Hospital, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bongioanni+MR%22">Bongioanni MR</searchLink>; Department of Neurology, SS Annunziata Hospital, Savigliano, Italy.<br /><searchLink fieldCode="AU" term="%22Toni+D%22">Toni D</searchLink>; Department of Human Neurosciences, University of Rome La Sapienza, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ricci+S%22">Ricci S</searchLink>; Department of Neurology, Città di Castello Hospital, Città di Castello, Italy.; Coordinatore Comitato Scientifico ISA-AII, Italy.<br /><searchLink fieldCode="AU" term="%22Sacco+S%22">Sacco S</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Ornello+R%22">Ornello R</searchLink>; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
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  Data: <searchLink fieldCode="CA" term="%22READAPT+Study+Group%22">READAPT Study Group</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229506311%22">European journal of neurology</searchLink> [Eur J Neurol] 2025 Apr; Vol. 32 (4), pp. e70163.
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  Data: Journal Article; Observational Study; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9506311 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1468-1331 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213515101%22">13515101 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Neurol <i>Subsets: </i>MEDLINE
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        Value: 10.1111/ene.70163
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      – Code: eng
        Text: English
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        StartPage: e70163
    Titles:
      – TitleFull: Real-World Dual Antiplatelet Therapy Use Exceeds Randomized Trials Boundaries With Possible Safety Issues in Patients With Large Artery Atherosclerosis-Insights From the READAPT Study.
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              Text: 2025 Apr
              Type: published
              Y: 2025
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              Value: 1468-1331
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              Value: 32
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              Value: 4
          Titles:
            – TitleFull: European journal of neurology
              Type: main
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