Bioinformatics analysis reveals CTSF suppresses tumor cell malignant phenotype and CD8 + T cell exhaustion by downregulating Bcl- 2 protein in the microenvironment of bladder cancer.

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Title: Bioinformatics analysis reveals CTSF suppresses tumor cell malignant phenotype and CD8 + T cell exhaustion by downregulating Bcl- 2 protein in the microenvironment of bladder cancer.
Authors: Gao D; Department of Urology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Beilin District, Xi'an, 710065, Shannxi Province, China., Yin J; Department of Urology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Beilin District, Xi'an, 710065, Shannxi Province, China., Tie P; Department of Urology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Beilin District, Xi'an, 710065, Shannxi Province, China., Liu Q; Department of Urology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Beilin District, Xi'an, 710065, Shannxi Province, China., Xue M; Department of Urology, Shaanxi Provincial People's Hospital, 256 Youyi West Road, Beilin District, Xi'an, 710065, Shannxi Province, China. xxxxxxxmx1@163.com.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Oct; Vol. 398 (10), pp. 14273-14289. Date of Electronic Publication: 2025 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-1912
DOI:10.1007/s00210-025-04189-6