Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.

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Title: Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.
Authors: Di Liberto G; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Egervari K; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Vogrig A; Department of Medicine (DMED), University of Udine, Udine, Italy.; Clinical Neurology, Department of Head-Neck and Neuroscience, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy., Spatola M; Neuroimmunology Program, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Hospital Clinic, University of Barcelona and Caixa Research Institute (CRI), Barcelona, Spain., Piccinno M; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Vincenti I; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Wagner I; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Kreutzfeldt M; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Endmayr V; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria., Ostertag K; Department of Neurology, Clinic Hietzing, Vienna, Austria., Rahimi J; Department of Neurology and Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders Klinik Donaustadt, Vienna, Austria., Vicino A; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Pröbstel AK; Department of Neurology and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.; Center of Neurology, Department of Neuroimmunology, University Hospital and University Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Meyronet D; Institute of Neuropathology, Hospices Civils de Lyon, 69008, Lyon, France.; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, CEDEX 08, 69373, Lyon, France.; Université de Lyon, Université Claude Bernard Lyon 1, CEDEX 08, 69373, Lyon, France., Frank S; Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland., Prinz M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Hewer E; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Brouland JP; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., de Leval L; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Parkkinen L; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Draganski B; Universitätsklinik für Neurologie, Inselspital, University of Bern, Bern, Switzerland.; University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland., Desestret V; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France., Dubey D; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA., Pittock SJ; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA., Roemer SF; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Höftberger R; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria., Irani SR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Autoimmune Neurology Group, West Wing, Level 3, John Radcliffe Hospital, University of Oxford, Oxford, UK., Honnorat J; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France., Du Pasquier R; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Merkler D; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland. doron.merkler@unige.ch.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland. doron.merkler@unige.ch.
Source: Acta neuropathologica [Acta Neuropathol] 2025 Apr 25; Vol. 149 (1), pp. 35. Date of Electronic Publication: 2025 Apr 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1432-0533
DOI:10.1007/s00401-025-02882-7