Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.

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Title: Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.
Authors: Di Liberto G; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Egervari K; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Vogrig A; Department of Medicine (DMED), University of Udine, Udine, Italy.; Clinical Neurology, Department of Head-Neck and Neuroscience, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy., Spatola M; Neuroimmunology Program, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Hospital Clinic, University of Barcelona and Caixa Research Institute (CRI), Barcelona, Spain., Piccinno M; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Vincenti I; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Wagner I; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Kreutzfeldt M; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland., Endmayr V; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria., Ostertag K; Department of Neurology, Clinic Hietzing, Vienna, Austria., Rahimi J; Department of Neurology and Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders Klinik Donaustadt, Vienna, Austria., Vicino A; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Pröbstel AK; Department of Neurology and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.; Center of Neurology, Department of Neuroimmunology, University Hospital and University Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany., Meyronet D; Institute of Neuropathology, Hospices Civils de Lyon, 69008, Lyon, France.; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, CEDEX 08, 69373, Lyon, France.; Université de Lyon, Université Claude Bernard Lyon 1, CEDEX 08, 69373, Lyon, France., Frank S; Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland., Prinz M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Hewer E; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Brouland JP; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., de Leval L; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Parkkinen L; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Draganski B; Universitätsklinik für Neurologie, Inselspital, University of Bern, Bern, Switzerland.; University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland., Desestret V; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France., Dubey D; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA., Pittock SJ; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA., Roemer SF; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA., Höftberger R; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria., Irani SR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Autoimmune Neurology Group, West Wing, Level 3, John Radcliffe Hospital, University of Oxford, Oxford, UK., Honnorat J; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France., Du Pasquier R; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Merkler D; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland. doron.merkler@unige.ch.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland. doron.merkler@unige.ch.
Source: Acta neuropathologica [Acta Neuropathol] 2025 Apr 25; Vol. 149 (1), pp. 35. Date of Electronic Publication: 2025 Apr 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens.
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  Data: <searchLink fieldCode="AU" term="%22Di+Liberto+G%22">Di Liberto G</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Egervari+K%22">Egervari K</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vogrig+A%22">Vogrig A</searchLink>; Department of Medicine (DMED), University of Udine, Udine, Italy.; Clinical Neurology, Department of Head-Neck and Neuroscience, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Spatola+M%22">Spatola M</searchLink>; Neuroimmunology Program, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Hospital Clinic, University of Barcelona and Caixa Research Institute (CRI), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Piccinno+M%22">Piccinno M</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vincenti+I%22">Vincenti I</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wagner+I%22">Wagner I</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kreutzfeldt+M%22">Kreutzfeldt M</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Endmayr+V%22">Endmayr V</searchLink>; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ostertag+K%22">Ostertag K</searchLink>; Department of Neurology, Clinic Hietzing, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Rahimi+J%22">Rahimi J</searchLink>; Department of Neurology and Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders Klinik Donaustadt, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Vicino+A%22">Vicino A</searchLink>; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pröbstel+AK%22">Pröbstel AK</searchLink>; Department of Neurology and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel and University of Basel, Basel, Switzerland.; Departments of Biomedicine and Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland.; Center of Neurology, Department of Neuroimmunology, University Hospital and University Bonn, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Meyronet+D%22">Meyronet D</searchLink>; Institute of Neuropathology, Hospices Civils de Lyon, 69008, Lyon, France.; Centre de Recherche en Cancérologie de Lyon, Inserm U1052, CNRS UMR5286, CEDEX 08, 69373, Lyon, France.; Université de Lyon, Université Claude Bernard Lyon 1, CEDEX 08, 69373, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Frank+S%22">Frank S</searchLink>; Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Prinz+M%22">Prinz M</searchLink>; Institute of Neuropathology, University of Freiburg, Freiburg, Germany.; Signaling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hewer+E%22">Hewer E</searchLink>; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brouland+JP%22">Brouland JP</searchLink>; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22de+Leval+L%22">de Leval L</searchLink>; Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Parkkinen+L%22">Parkkinen L</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Draganski+B%22">Draganski B</searchLink>; Universitätsklinik für Neurologie, Inselspital, University of Bern, Bern, Switzerland.; University Institute for Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Desestret+V%22">Desestret V</searchLink>; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Dubey+D%22">Dubey D</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pittock+SJ%22">Pittock SJ</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Roemer+SF%22">Roemer SF</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.<br /><searchLink fieldCode="AU" term="%22Höftberger+R%22">Höftberger R</searchLink>; Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.; Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Irani+SR%22">Irani SR</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Autoimmune Neurology Group, West Wing, Level 3, John Radcliffe Hospital, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Honnorat+J%22">Honnorat J</searchLink>; French Reference Center On Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis, Hospices Civils de Lyon, MeLiS - UCBL - CNRS UMR 5284 - INSERM U1314, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Du+Pasquier+R%22">Du Pasquier R</searchLink>; Department of Clinical Neurosciences, Neurology Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Merkler+D%22">Merkler D</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland. doron.merkler@unige.ch.; Division of Clinical Pathology, Geneva University Hospital, Geneva, Switzerland. doron.merkler@unige.ch.
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