Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: a prospective, single-centre, cohort study and analysis of transcriptomic predictors of response.
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| Title: | Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: a prospective, single-centre, cohort study and analysis of transcriptomic predictors of response. |
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| Authors: | Drennan PG; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: philip.drennan@ndorms.ox.ac.uk., Provine NM; Pandemic Sciences Institute, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Harris SA; Jenner Institute, University of Oxford, Oxford, UK., Otter A; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK., Hollett K; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Cooper C; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., De Maeyer RPH; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Nassanga B; Jenner Institute, University of Oxford, Oxford, UK., Ateere A; Jenner Institute, University of Oxford, Oxford, UK., Pudjohartono MF; Pandemic Sciences Institute, University of Oxford, Oxford, UK., Peng Y; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Chen JL; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Jones S; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK., Fadzillah NHM; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Grifoni A; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Sette A; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA., Satti I; Jenner Institute, University of Oxford, Oxford, UK., Murray SM; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK., Rowe C; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK., Mandal S; UK Health Security Agency, Colindale, UK., Hallis B; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Dong T; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Richards D; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Fullerton J; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., McShane H; Jenner Institute, University of Oxford, Oxford, UK., Coles M; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. |
| Source: | The Lancet. Microbe [Lancet Microbe] 2025 Jun; Vol. 6 (6), pp. 101045. Date of Electronic Publication: 2025 Apr 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101769019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-5247 (Electronic) Linking ISSN: 26665247 NLM ISO Abbreviation: Lancet Microbe Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40286799 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: a prospective, single-centre, cohort study and analysis of transcriptomic predictors of response. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Drennan+PG%22">Drennan PG</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Electronic address: philip.drennan@ndorms.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Provine+NM%22">Provine NM</searchLink>; Pandemic Sciences Institute, University of Oxford, Oxford, UK; Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Harris+SA%22">Harris SA</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Otter+A%22">Otter A</searchLink>; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK.<br /><searchLink fieldCode="AU" term="%22Hollett+K%22">Hollett K</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cooper+C%22">Cooper C</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22De+Maeyer+RPH%22">De Maeyer RPH</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Nassanga+B%22">Nassanga B</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ateere+A%22">Ateere A</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Pudjohartono+MF%22">Pudjohartono MF</searchLink>; Pandemic Sciences Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Chen+JL%22">Chen JL</searchLink>; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jones+S%22">Jones S</searchLink>; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK.<br /><searchLink fieldCode="AU" term="%22Fadzillah+NHM%22">Fadzillah NHM</searchLink>; Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Grifoni+A%22">Grifoni A</searchLink>; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sette+A%22">Sette A</searchLink>; Center for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Satti+I%22">Satti I</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Murray+SM%22">Murray SM</searchLink>; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK.<br /><searchLink fieldCode="AU" term="%22Rowe+C%22">Rowe C</searchLink>; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK.<br /><searchLink fieldCode="AU" term="%22Mandal+S%22">Mandal S</searchLink>; UK Health Security Agency, Colindale, UK.<br /><searchLink fieldCode="AU" term="%22Hallis+B%22">Hallis B</searchLink>; Emerging Pathogen Serology Group, UK Health Security Agency, Porton Down, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dong+T%22">Dong T</searchLink>; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK; MRC Translational Immune Discovery Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Richards+D%22">Richards D</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Fullerton+J%22">Fullerton J</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McShane+H%22">McShane H</searchLink>; Jenner Institute, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Coles+M%22">Coles M</searchLink>; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101769019%22">The Lancet. Microbe</searchLink> [Lancet Microbe] 2025 Jun; Vol. 6 (6), pp. 101045. <i>Date of Electronic Publication: </i>2025 Apr 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101769019 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2666-5247 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226665247%22">26665247 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Microbe <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40286799 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.lanmic.2024.101045 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 101045 Titles: – TitleFull: Immunogenicity of MVA-BN vaccine deployed as mpox prophylaxis: a prospective, single-centre, cohort study and analysis of transcriptomic predictors of response. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Drennan PG – PersonEntity: Name: NameFull: Provine NM – PersonEntity: Name: NameFull: Harris SA – PersonEntity: Name: NameFull: Otter A – PersonEntity: Name: NameFull: Hollett K – PersonEntity: Name: NameFull: Cooper C – PersonEntity: Name: NameFull: De Maeyer RPH – PersonEntity: Name: NameFull: Nassanga B – PersonEntity: Name: NameFull: Ateere A – PersonEntity: Name: NameFull: Pudjohartono MF – PersonEntity: Name: NameFull: Peng Y – PersonEntity: Name: NameFull: Chen JL – PersonEntity: Name: NameFull: Jones S – PersonEntity: Name: NameFull: Fadzillah NHM – PersonEntity: Name: NameFull: Grifoni A – PersonEntity: Name: NameFull: Sette A – PersonEntity: Name: NameFull: Satti I – PersonEntity: Name: NameFull: Murray SM – PersonEntity: Name: NameFull: Rowe C – PersonEntity: Name: NameFull: Mandal S – PersonEntity: Name: NameFull: Hallis B – PersonEntity: Name: NameFull: Klenerman P – PersonEntity: Name: NameFull: Dong T – PersonEntity: Name: NameFull: Richards D – PersonEntity: Name: NameFull: Fullerton J – PersonEntity: Name: NameFull: McShane H – PersonEntity: Name: NameFull: Coles M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2025 Jun Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2666-5247 Numbering: – Type: volume Value: 6 – Type: issue Value: 6 Titles: – TitleFull: The Lancet. Microbe Type: main |
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