MUC1-C dependency in drug resistant HR+/HER2- breast cancer identifies a new target for antibody-drug conjugate treatment.

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Title: MUC1-C dependency in drug resistant HR+/HER2- breast cancer identifies a new target for antibody-drug conjugate treatment.
Authors: Nakashoji A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Bhattacharya A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Ozawa H; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Haratake N; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Shigeta K; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Fushimi A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Yamashita N; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Matsui A; Department of Breast Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan., Kure S; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Kameyama T; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Takeuchi M; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Fukuda K; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Yokoe T; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Nagayama A; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Hayahsida T; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Kitagawa Y; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Liu R; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Giordano A; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Jeselsohn R; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Shapiro GI; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Kufe D; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Donald_Kufe@dfci.harvard.edu.
Source: NPJ breast cancer [NPJ Breast Cancer] 2025 Apr 26; Vol. 11 (1), pp. 39. Date of Electronic Publication: 2025 Apr 26.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2374-4677
DOI:10.1038/s41523-025-00751-w