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Resistance and resilience to Alzheimer's disease in Down syndrome.

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Title: Resistance and resilience to Alzheimer's disease in Down syndrome.
Authors: Boyle R; Penn Frontotemporal Degeneration Center, Perelman School of Medicine, Richards Medical Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Koops EA; Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ances B; Department of Neurology, Center for Advanced Medicine Neuroscience Center, Washington University in St. Louis, St. Louis, Missouri, USA., Andrews EJ; Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA., Arenaza-Urquijo EM; Barcelona Institute for Global Health, Environment and Health Over the Life Course Programme, Climate, Air Pollution, Nature and Urban Health Programme, Pompeu Fabra University Carrer de la Mercè, Rosselló, Barcelona, Spain., Bejanin A; Sant Pau Memory Unit, Department of Neurology, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain.; Center of Biomedical Investigation Network for Neurodegenerative Diseases, Planta, Madrid, Spain., Brickman AM; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, G.H. Sergievsky Center, Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA., Buckley RF; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Clas GS; Laboratory of Neurodegenerative Diseases, Institute of Neurosciences, Foundation for the Fight Against Childhood Neurological Diseases (LEN-INEU-Fleni-CONICET), Fleni, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina., Costello E; Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Coughlan GT; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Conley AC; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Deng F; School of Psychology, Shenzhen University, Shenzhen, China., de Paula Faria D; Laboratory of Nuclear Medicine (LIM43), Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil., Edwards N; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, G.H. Sergievsky Center, Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA., Flores-Aguilar L; Department of Pathology and Laboratory Medicine, University of California, Irvine, California, USA., Fortea J; Sant Pau Memory Unit, Department of Neurology, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas. CIBERNED, Barcelona, Spain.; Barcelona Down Medical Center, Fundació Catalana Síndrome de Down, Barcelona, Spain., Ghazi Saidi L; Department of Speech Language Pathology, University of Nebraska at Kearney, Kearney, Nebraska, USA., Head E; Department of Pathology & Laboratory Medicine and Neurology, University of California, Irvine, California, USA., Hom CL; Department of Psychiatry & Human Behavior, University of California, Irvine, California, USA., Koenig K; Imaging Sciences, Diagnostics Institute, Cleveland Clinic, Cleveland, Ohio, USA., Lao P; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, G.H. Sergievsky Center, Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA., Lengyel I; The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Li YJ; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA., Loi S; Department of Psychiatry, University of Melbourne; Neuropsychiatry Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia., Loughrey D; School of Nursing, Psychotherapy and Community Health, Dublin City University, Dublin, Ireland.; Global Brain Health Institute, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.; GBHI Memory and Aging Center, University of California, San Francisco, San Francisco, California, USA., McGlinchey E; Global Brain Health Institute, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.; GBHI Memory and Aging Center, University of California, San Francisco, San Francisco, California, USA.; Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Dublin, Ireland., Newhouse P; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Health System, Nashville, Tennessee, USA., Pertierra L; Global Brain Health Institute, Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.; GBHI Memory and Aging Center, University of California, San Francisco, San Francisco, California, USA.; Cognitive Neurology, Neuropsychology and Neuropsychiatry Unit, Buenos Aires, Argentina., Prokopiou PC; Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Qi Q; Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., de Paula França Resende E; Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Russell J; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Scanlon CE; Department of Psychological and Brain Sciences, Drexel University, Philadelphia, Pennsylvania, USA., Schneider C; Department of Neurology, Inselspital and University of Bern, Rosenbühlgasse, Bern, Switzerland., Schultz SA; Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Seto M; Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Shaka S; Department of Neurology, University of California, Irvine, Irvine, California, USA., Soldan A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Vaqué Alcázar L; Sant Pau Memory Unit, Department of Neurology, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain., Weng Y; Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., Wilson JE; Center for Cognitive Medicine, Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Geriatric Research, Education, and Clinical Center, Veterans Affairs Tennessee Valley Health System, Nashville, Tennessee, USA., Zaman SH; Department of Psychiatry, School of Medicine, University of Cambridge, Cambridge, UK., Zsadányi SE; Sant Pau Memory Unit, Department of Neurology, Biomedical Research Institute Sant Pau, Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, Barcelona, Spain., Hartley S; School of Human Ecology and Waisman Center, Nancy Nicholas Hall, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70151.
Publication Type: Journal Article; Review
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1552-5279
DOI:10.1002/alz.70151