Glutamine limits NLRP3 inflammasome activation and pyroptosis in macrophages by sustaining the IRG1/itaconate axis.
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| Title: | Glutamine limits NLRP3 inflammasome activation and pyroptosis in macrophages by sustaining the IRG1/itaconate axis. |
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| Authors: | Chen X; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Zhu Y; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Xia L; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Su S; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Fan S; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Lu Y; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Chen Q; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Wei Y; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Huang Q; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Liu X; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Peng X; Clinical Medical Research Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.; State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. |
| Source: | The FEBS journal [FEBS J] 2025 Nov; Vol. 292 (22), pp. 6016-6034. Date of Electronic Publication: 2025 Apr 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1742-4658 |
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| DOI: | 10.1111/febs.70119 |
