Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9.
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| Title: | Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9. |
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| Authors: | Daniels MH; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Castro J; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Lee YT; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Gotur D; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Knockenhauer KE; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Grigoriu S; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Lockbaum GJ; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Cheong JE; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Lu C; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Brennan D; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Buker SM; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Liu J; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Yao S; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Sparling BA; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Sickmier EA; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Ribich S; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Blakemore SJ; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Silver SJ; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Boriack-Sjodin PA; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Duncan KW; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States., Copeland RA; Accent Therapeutics, Inc., 1050 Waltham Street, Lexington, Massachusetts 02421, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2025 May 08; Vol. 68 (9), pp. 9537-9554. Date of Electronic Publication: 2025 Apr 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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