Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE.

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Title: Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE.
Authors: Liu Y; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA., Brown CM; School of Life Sciences and Department of Chemistry, University of Warwick, Coventry, UK.; Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh, The Netherlands., Borges N; Instituto de Tecnologia Química e Biológica António Xavier, ITQB NOVA, Universidade Nova de Lisboa, Oeiras, Portugal.; Marine and Environmental Sciences Centre, Escola Superior de Tecnologia, Instituto Politécnico de Setúbal, Setúbal, Portugal., Nobre RN; Instituto de Tecnologia Química e Biológica António Xavier, ITQB NOVA, Universidade Nova de Lisboa, Oeiras, Portugal., Erramilli S; Department of Biochemistry and Molecular Biophysics, University of Chicago, Chicago, IL, USA., Belcher Dufrisne M; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.; Department of Chemistry, University of Virginia, Charlottesville, VA, USA., Kloss B; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA., Giacometti S; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.; School of Medicine, New York University, New York, NY, USA., Esteves AM; Instituto de Tecnologia Química e Biológica António Xavier, ITQB NOVA, Universidade Nova de Lisboa, Oeiras, Portugal., Timóteo CG; Instituto de Tecnologia Química e Biológica António Xavier, ITQB NOVA, Universidade Nova de Lisboa, Oeiras, Portugal., Tokarz P; Department of Biochemistry and Molecular Biophysics, University of Chicago, Chicago, IL, USA., Cater RJ; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA.; Institute for Molecular Bioscience, The University of Queensland, St. Lucia, QLD, Australia., Lowary TL; Institute of Biological Chemistry, Academia Sinica, Nangang, Taipei, Taiwan.; Department of Chemistry, University of Alberta, Edmonton, AB, Canada.; Institute of Biochemical Sciences, National Taiwan University, Taipei, Taiwan., Morita YS; Department of Microbiology, University of Massachusetts, Amherst, MA, USA., Kossiakoff AA; Department of Biochemistry and Molecular Biophysics, University of Chicago, Chicago, IL, USA., Santos H; Instituto de Tecnologia Química e Biológica António Xavier, ITQB NOVA, Universidade Nova de Lisboa, Oeiras, Portugal. santos@itqb.unl.pt., Stansfeld PJ; School of Life Sciences and Department of Chemistry, University of Warwick, Coventry, UK. Phillip.Stansfeld@warwick.ac.uk., Nygaard R; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA. rin7007@med.cornell.edu.; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA. rin7007@med.cornell.edu., Mancia F; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, USA. fm123@cumc.columbia.edu.
Source: Nature communications [Nat Commun] 2025 Apr 29; Vol. 16 (1), pp. 3974. Date of Electronic Publication: 2025 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-57843-1