Cdkn1a silencing restores myoblast differentiation by inducing selective apoptosis in senescent cells.

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Title: Cdkn1a silencing restores myoblast differentiation by inducing selective apoptosis in senescent cells.
Authors: Kim S; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea., Gu B; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea.; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea., So CY; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea.; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea., Mantik KEK; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea.; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea., Jung SH; Department of Biochemistry, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Integrated Research Center for Genomic Polymorphism, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Department of Medical Sciences, Graduate School of The Catholic University of Korea, Seoul, Republic of Korea., Moon S; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea., Park DH; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea.; Department of Kinesiology, Inha University, Incheon, Republic of Korea., Kwak HB; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea.; Department of Kinesiology, Inha University, Incheon, Republic of Korea., Cho J; College of Sport Science, Sungkyunkwan University, Suwon, Republic of Korea., Cho EJ; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea.; Department of Kinesiology, Inha University, Incheon, Republic of Korea., Lee JS; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea. jaseslee@inha.ac.kr.; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea. jaseslee@inha.ac.kr.; Department of Molecular Medicine, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea. jaseslee@inha.ac.kr., Kang JH; Department of Pharmacology, Inha University College of Medicine, 100, Inha-Ro, Michuhol-Gu, Incheon, 22212, Republic of Korea. johykang@inha.ac.kr.; Research Center for Controlling Intercellular Communication, Inha University College of Medicine, Incheon, 22212, Republic of Korea. johykang@inha.ac.kr.; Program in Biomedical Science and Engineering, Inha University, Incheon, South Korea. johykang@inha.ac.kr.
Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2025 Apr 30; Vol. 30 (1), pp. 53. Date of Electronic Publication: 2025 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1689-1392
DOI:10.1186/s11658-025-00731-9