Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.
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| Title: | Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial. |
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| Authors: | Oshima K; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Di Gravio C; Department of Biostatistics., Yan B; Department of Biostatistics., McMurtry SA; Department of Medicine and., Burke R; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Levoir LM; Department of Biostatistics., Kravitz MS; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Stephenson D; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Issaian A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Douglas IS; Department of Medicine and.; Department of Medicine, Denver Health Medical Center, Denver, Colorado; and., Self WH; Vanderbilt Institute for Clinical and Translational Research, and.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Lindsell CJ; Department of Biostatistics and Bioinformatics and the Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina., Schildcrout JS; Department of Biostatistics., Schmidt EP; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts. |
| Source: | Annals of the American Thoracic Society [Ann Am Thorac Soc] 2025 Sep; Vol. 22 (9), pp. 1382-1393. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III |
| Journal Info: | Publisher: American Thoracic Society Country of Publication: England NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2325-6621 |
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| DOI: | 10.1513/AnnalsATS.202501-012OC |