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Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.

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Title: Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.
Authors: Oshima K; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Di Gravio C; Department of Biostatistics., Yan B; Department of Biostatistics., McMurtry SA; Department of Medicine and., Burke R; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Levoir LM; Department of Biostatistics., Kravitz MS; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Stephenson D; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Issaian A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado., Douglas IS; Department of Medicine and.; Department of Medicine, Denver Health Medical Center, Denver, Colorado; and., Self WH; Vanderbilt Institute for Clinical and Translational Research, and.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Lindsell CJ; Department of Biostatistics and Bioinformatics and the Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina., Schildcrout JS; Department of Biostatistics., Schmidt EP; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Source: Annals of the American Thoracic Society [Ann Am Thorac Soc] 2025 Sep; Vol. 22 (9), pp. 1382-1393.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial.
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  Data: <searchLink fieldCode="AU" term="%22Oshima+K%22">Oshima K</searchLink>; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Di+Gravio+C%22">Di Gravio C</searchLink>; Department of Biostatistics.<br /><searchLink fieldCode="AU" term="%22Yan+B%22">Yan B</searchLink>; Department of Biostatistics.<br /><searchLink fieldCode="AU" term="%22McMurtry+SA%22">McMurtry SA</searchLink>; Department of Medicine and.<br /><searchLink fieldCode="AU" term="%22Burke+R%22">Burke R</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Levoir+LM%22">Levoir LM</searchLink>; Department of Biostatistics.<br /><searchLink fieldCode="AU" term="%22Kravitz+MS%22">Kravitz MS</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Stephenson+D%22">Stephenson D</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Issaian+A%22">Issaian A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Hansen+KC%22">Hansen KC</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Douglas+IS%22">Douglas IS</searchLink>; Department of Medicine and.; Department of Medicine, Denver Health Medical Center, Denver, Colorado; and.<br /><searchLink fieldCode="AU" term="%22Self+WH%22">Self WH</searchLink>; Vanderbilt Institute for Clinical and Translational Research, and.; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Lindsell+CJ%22">Lindsell CJ</searchLink>; Department of Biostatistics and Bioinformatics and the Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina.<br /><searchLink fieldCode="AU" term="%22Schildcrout+JS%22">Schildcrout JS</searchLink>; Department of Biostatistics.<br /><searchLink fieldCode="AU" term="%22Schmidt+EP%22">Schmidt EP</searchLink>; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Shapiro+NI%22">Shapiro NI</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Thoracic+Society%22">American Thoracic Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101600811 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2325-6621 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223256621%22">23256621 </searchLink><i>NLM ISO Abbreviation: </i>Ann Am Thorac Soc <i>Subsets: </i>MEDLINE
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