SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data.

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Title: SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data.
Authors: Zhang D; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA., Segerstolpe Å; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Slyper M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, 1 DNA Way, South San Francisco, CA, USA., Waldman J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Murray E; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Strasser R; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Watter J; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Cohen O; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University, Beersheba, Israel., Ashenberg O; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Abravanel D; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Jané-Valbuena J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, 1 DNA Way, South San Francisco, CA, USA., Mages S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany., Lako A; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Helvie K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Rozenblatt-Rosen O; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, 1 DNA Way, South San Francisco, CA, USA., Rodig S; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Chen F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts Institute of Technology, Cambridge, MA, USA., Wagle N; Broad Institute of MIT and Harvard, Cambridge, MA, USA. wagle.nikhil@gene.com.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. wagle.nikhil@gene.com.; Genentech, 1 DNA Way, South San Francisco, CA, USA. wagle.nikhil@gene.com., Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Massachusetts Institute of Technology, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Genentech, 1 DNA Way, South San Francisco, CA, USA. aviv.regev.sc@gmail.com., Klughammer J; Broad Institute of MIT and Harvard, Cambridge, MA, USA. klughammer@genzentrum.lmu.de.; Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany. klughammer@genzentrum.lmu.de.
Source: Genome biology [Genome Biol] 2025 May 02; Vol. 26 (1), pp. 112. Date of Electronic Publication: 2025 May 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-760X
DOI:10.1186/s13059-025-03573-y