Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function.

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Title: Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function.
Authors: Paillard M; Laboratoire CarMeN-IRIS Team, INSERM, INRA, Université Claude Bernard Lyon-1, Bron, France., Abdellatif M; Division of Cardiology, Department of Internal Medicine, Medical University of Graz, BioTechMed Graz, Graz, Austria., Andreadou I; Laboratory of Pharmacology, School of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece., Bär C; Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Germany-Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., Bertrand L; UCLouvain, Institute for Experimental and Clinical Research, Pole of Cardiovascular Research; WELBIO Department, WEL Research Institute, Brussels, Belgium., Brundel BJJM; Physiology, Amsterdam UMC Location Vrije Universiteit, Cardiovascular Sciences, Heart Failure and Arrhythmias, Amsterdam, The Netherlands., Chiva-Blanch G; Faculty of Health Sciences, Universitat Oberta de Catalunya, Department of Endocrinology and Nutrition, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Hospital Clínic of Barcelona, Barcelona, Spain.; Biomedical Network Research Centre on Obesity and Nutrition Physiopathology (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain., Davidson SM; The Hatter Cardiovascular Institute, University College London, London, UK., Dawson D; Aberdeen Cardiovascular and Diabetes Centre, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK., Di Lisa F; Department of Biomedical Sciences, University of Padua, Padova, Italy., Evans P; William Harvey Research Institute, Queen Mary University of London, London, UK., Giricz Z; Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary., Hausenloy DJ; The Hatter Cardiovascular Institute, University College London, London, UK.; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University Singapore, Singapore, Singapore., Kleinbongard P; Institute of Pathophysiology, Faculty of Medicine University of Duisburg-Essen, Duisburg, Germany., Lezoualc'h F; Institute of Metabolic and Cardiovascular Diseases (I2MC), INSERM, University of Toulouse III - Paul Sabatier, Toulouse, France., Liehn E; Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Translational Research, Comprehensive Heart Failure Center (CHFC), and Medical Clinic I, University Clinic Würzburg, Würzburg, Germany., Maack C; Department of Translational Research, Comprehensive Heart Failure Center (CHFC), and Medical Clinic I, University Clinic Würzburg, Würzburg, Germany., Maguy A; Atrial Fibrillation and Therapeutic Innovation, Department of Physiology, Faculty of Medicine, University of Bern, Bern, Switzerland., Murphy E; Cardiac Physiology, NHLBI, NIH, Bethesda, MD, USA., Perrino C; Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy., Pesce M; Unit of Cardiovascular Tissue Engineering, Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Cell Biology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.; Department of Mechanical and Aerospace Engineering (DIMEAS), Turin School of Engineering, Turin, Italy., Rainer PP; Division of Cardiology, Department of Internal Medicine, Medical University of Graz, BioTechMed Graz, Graz, Austria., Streckfuss-Bömeke K; Institute of Pharmacology and Toxicology, University of Würzburg, Germany-Clinic for Cardiology and Pneumology, University Medicine Göttingen, and German Center for Cardiovascular Research (DZHK), Partner site Göttingen, Göttingen, Germany., Thielmann M; West-German Heart & Vascular Center, University Duisburg-Essen, Essen, Germany., Tian R; Mitochondria and Metabolism Center, Department of Anesthesiology & Pain Medicine, University of Washington, Seattle, WA, USA., Tocchetti CG; Department of Translational Medical Sciences, Center for Basic and Clinical Immunology Research, Interdepartmental Center of Clinical and Translational Sciences, Interdepartmental Hypertension Research Center, Federico II University, Naples, Italy., Van Der Velden J; Department of Physiology, Amsterdam UMC, Vrije Universiteit Amsterdam, The Netherlands-Amsterdam Cardiovascular Sciences, Heart Failure & Arrhythmias, Amsterdam, The Netherlands., Van Linthout S; Berlin Institute of Health (BIH) at Charité, Universitätmedizin Berlin, Germany, BIH Center for Regenerative Therapies (BCRT), German Center for Cardiovascular Research (DZHK), Partner site Berlin, Berlin, Germany., Zacchigna S; Laboratory of Cardiovascular Biology, The International Centre for Genetic Engineering and Biotechnology, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Krieg T; Department of Medicine, University of Cambridge, Cambridge, UK.
Source: European journal of heart failure [Eur J Heart Fail] 2025 Sep; Vol. 27 (9), pp. 1720-1736. Date of Electronic Publication: 2025 May 04.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 100887595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0844 (Electronic) Linking ISSN: 13889842 NLM ISO Abbreviation: Eur J Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1879-0844
DOI:10.1002/ejhf.3674