Dual inhibition of TGFβ and PDGF improves RV remodeling and function in response to RV pressure or volume-loading.
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| Title: | Dual inhibition of TGFβ and PDGF improves RV remodeling and function in response to RV pressure or volume-loading. |
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| Authors: | Dauz JD; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Yazaki K; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Akazawa Y; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Meister TA; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Kabir G; Li Ka Shing Knowledge Institute, Keenan Research Centre, St. Michael's Hospital, Toronto, Ontario, Canada., Kadowaki S; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Honjo O; Division of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada., Heximer SP; Department of Physiology, University of Toronto, Toronto, Ontario, Canada., Wald RM; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, Toronto, Ontario, Canada., Connelly KA; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Li Ka Shing Knowledge Institute, Keenan Research Centre, St. Michael's Hospital, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada., Friedberg MK; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.; Division of Cardiology, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada. |
| Source: | Physiological reports [Physiol Rep] 2025 May; Vol. 13 (9), pp. e70339. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM ID: 101607800 Publication Model: Print Cited Medium: Internet ISSN: 2051-817X (Electronic) Linking ISSN: 2051817X NLM ISO Abbreviation: Physiol Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2051-817X |
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| DOI: | 10.14814/phy2.70339 |
