Muscadine Grape Skin Extract in Biochemically Recurrent Prostate Cancer: A Randomized, Placebo-Controlled, Biomarker-Enriched Trial in Patients With the SOD2 Ala/Ala Variant.

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Title: Muscadine Grape Skin Extract in Biochemically Recurrent Prostate Cancer: A Randomized, Placebo-Controlled, Biomarker-Enriched Trial in Patients With the SOD2 Ala/Ala Variant.
Authors: Mandl A; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Zahurak ML; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Metri NA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Shore ND; Carolina Urologic Research Center, Myrtle Beach, SC, USA., Mao S; Allegheny Health Network, Pittsburgh, PA, USA., McKay RR; University of California, San Diego, La Jolla, CA, USA., Taplin ME; Dana-Farber Cancer Institute, Boston, MA, USA., Szmulewitz RZ; University of Chicago Medical Center, Chicago, IL, USA., Maughan BL; Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA., Reichert ZR; University of Michigan Medical School, Ann Arbor, MI, USA., Kessler ER; University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, CO, USA., Heath EI; Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA., Dreicer R; University of Virginia School of Medicine, Charlottesville, VA, USA., Stein CA; City of Hope Medical Center, Madras, OR, USA., Milne GL; Vanderbilt University Medical Center, Nashville, TN, USA., Sfanos KS; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ernst SE; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mummert LA; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Cruz-Lebrón A; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Michel SLJ; University of Maryland, College Park, MD, USA., Kane MA; University of Maryland, College Park, MD, USA., Hursey M; University of Maryland, College Park, MD, USA., Worth MA; University of Maryland, College Park, MD, USA., Wagner WD; Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Muscadine Naturals Inc., Clemmons, NC, USA., Eshleman JR; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Debeljak M; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Xu L; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Cao H; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Dowling D; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Marshall CH; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Markowski MC; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Denmeade SR; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Eisenberger MA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Antonarakis ES; University of Minnesota, Masonic Cancer Center, Minneapolis, MN, USA., Carducci MA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA., Paller CJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USA.
Source: The Prostate [Prostate] 2025 Jul; Vol. 85 (10), pp. 966-976. Date of Electronic Publication: 2025 May 05.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8101368 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0045 (Electronic) Linking ISSN: 02704137 NLM ISO Abbreviation: Prostate Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1097-0045
DOI:10.1002/pros.24903