Sodium aescinate promotes apoptosis of pancreatic stellate cells and alleviates pancreatic fibrosis by inhibiting the PI3K/Akt/FOXO1 signaling pathways.
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| Title: | Sodium aescinate promotes apoptosis of pancreatic stellate cells and alleviates pancreatic fibrosis by inhibiting the PI3K/Akt/FOXO1 signaling pathways. |
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| Authors: | Wang QY; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Xu BY; Department of Digestive Diseases, Huian County Hospital, Quanzhou, China., Wang Y; Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China., Lin YM; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Zheng LF; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Liu G; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Li DZ; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Jiang CS; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Wang W; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China., Zeng XP; Department of Digestive Diseases, Dongfang Hospital of Xiamen University, School of Medicine, Xiamen University, Fuzhou, China.; Department of Digestive Diseases, 900th Hospital of PLA Joint Logistic Support Force, Fuzhou, China.; Department of Digestive Diseases, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2025 Apr 22; Vol. 16, pp. 1554260. Date of Electronic Publication: 2025 Apr 22 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1663-9812 |
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| DOI: | 10.3389/fphar.2025.1554260 |
