Synthesis and in vivo biological characterization of six carbon-11 sigma-1 receptor radiotracers in rodent and nonhuman primate.

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Title: Synthesis and in vivo biological characterization of six carbon-11 sigma-1 receptor radiotracers in rodent and nonhuman primate.
Authors: Soda AK; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Huang T; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Zhou W; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Chen H; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Jiang H; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Jadhav SB; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Xing Z; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Yu Y; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Tian L; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Wong DF; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Perlmutter JS; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neuroscience, Programs in Physical Therapy and Occupational Therapy, Washington University School of Medicine, St. Louis, MO 63110, USA., Ni R; Institute for Regenerative Medicine, University of Zurich, Zurich, Switzerland; Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Zurich, Switzerland., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Tu Z; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: zhudetu@wustl.edu.
Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2025 Aug 15; Vol. 126, pp. 118218. Date of Electronic Publication: 2025 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1464-3391
DOI:10.1016/j.bmc.2025.118218