Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities.
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| Title: | Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities. |
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| Authors: | Zhao F; Department of Pediatric Neurosurgery, Beijing Key Laboratory of Drug Innovation for Neuro-Oncology, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. zhaofu@ccmu.edu.cn., Teng XF; National Genomics Data Center, China National Center for Bioinformation & Beijing Institute of Genomics, Chinese Academy of Sciences, No. 1 Beichen West Road, Chaoyang District, Beijing, 100101, People's Republic of China.; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA., Zhang J; Department of Neural Reconstruction, Beijing Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China., Li SW; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China., Wang LM; Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China., Zhao HG; Department of Pediatric Neurosurgery, Beijing Key Laboratory of Drug Innovation for Neuro-Oncology, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China., Zhang S; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.; Department of Neurosurgery, Beijing Hospital, Peking Union Medical College, Beijing, People's Republic of China., Zhao C; Department of Neuro-Oncology, Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China., Li P; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China., Zhao XB; Department of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China., Song SH; National Genomics Data Center, China National Center for Bioinformation & Beijing Institute of Genomics, Chinese Academy of Sciences, No. 1 Beichen West Road, Chaoyang District, Beijing, 100101, People's Republic of China. songshh@big.ac.cn., Liu PN; Department of Neural Reconstruction, Beijing Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. pinanliu@ccmu.edu.cn.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. pinanliu@ccmu.edu.cn. |
| Source: | Acta neuropathologica [Acta Neuropathol] 2025 May 09; Vol. 149 (1), pp. 47. Date of Electronic Publication: 2025 May 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40343504 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhao+F%22">Zhao F</searchLink>; Department of Pediatric Neurosurgery, Beijing Key Laboratory of Drug Innovation for Neuro-Oncology, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. zhaofu@ccmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Teng+XF%22">Teng XF</searchLink>; National Genomics Data Center, China National Center for Bioinformation & Beijing Institute of Genomics, Chinese Academy of Sciences, No. 1 Beichen West Road, Chaoyang District, Beijing, 100101, People's Republic of China.; Department of Neurology, Yale School of Medicine, New Haven, CT, 06511, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Neural Reconstruction, Beijing Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+SW%22">Li SW</searchLink>; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+LM%22">Wang LM</searchLink>; Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+HG%22">Zhao HG</searchLink>; Department of Pediatric Neurosurgery, Beijing Key Laboratory of Drug Innovation for Neuro-Oncology, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.; Department of Neurosurgery, Beijing Hospital, Peking Union Medical College, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Department of Neuro-Oncology, Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+XB%22">Zhao XB</searchLink>; Department of Nuclear Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Song+SH%22">Song SH</searchLink>; National Genomics Data Center, China National Center for Bioinformation & Beijing Institute of Genomics, Chinese Academy of Sciences, No. 1 Beichen West Road, Chaoyang District, Beijing, 100101, People's Republic of China. songshh@big.ac.cn.<br /><searchLink fieldCode="AU" term="%22Liu+PN%22">Liu PN</searchLink>; Department of Neural Reconstruction, Beijing Key Laboratory of Central Nervous System Injury, Beijing Neurosurgical Institute, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. pinanliu@ccmu.edu.cn.; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, 119 South 4th Ring West Road, Fengtai District, Beijing, 100070, People's Republic of China. pinanliu@ccmu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2025 May 09; Vol. 149 (1), pp. 47. <i>Date of Electronic Publication: </i>2025 May 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0412041 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0533 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200016322%22">00016322 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40343504 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00401-025-02883-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 47 Titles: – TitleFull: Multiplatform molecular analyses reveal two molecular subgroups of NF2-related schwannomatosis vestibular schwannomas with distinct tumour microenvironment and therapeutic vulnerabilities. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhao F – PersonEntity: Name: NameFull: Teng XF – PersonEntity: Name: NameFull: Zhang J – PersonEntity: Name: NameFull: Li SW – PersonEntity: Name: NameFull: Wang LM – PersonEntity: Name: NameFull: Zhao HG – PersonEntity: Name: NameFull: Zhang S – PersonEntity: Name: NameFull: Zhao C – PersonEntity: Name: NameFull: Li P – PersonEntity: Name: NameFull: Zhao XB – PersonEntity: Name: NameFull: Song SH – PersonEntity: Name: NameFull: Liu PN IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 05 Text: 2025 May 09 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1432-0533 Numbering: – Type: volume Value: 149 – Type: issue Value: 1 Titles: – TitleFull: Acta neuropathologica Type: main |
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